Videnskabelige publikationer 2015

Artikler og bogkapitler.​​

  1. Alanin MC, Johansen HK, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, von Buchwald C: Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia. Acta Otolaryngol. 135:58-63; 2015

  2. Alanin M, Nielsen KG, von Buchwald C, Skov M, Aasnæs K, Høiby N, Johansen HK: A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. Clin. Microbiol. Infect. 21:1093.e1-1093.e7; 2015

  3. Alhede M, Christensen LH, Bjarnsholt T: Microbial biofilms and adverse reactions to gel fillers used in cosmetic surgery. Adv. Exp. Med. Biol. 831:45-52; 2015

  4. Al-Sabi M, Gad J, Riber U, Kurtzhals J, Enemark H: New filtration system for efficient recovery of waterborne Cryptosporidium oocysts and Giardia cysts. J. Applied Microbiol. 119: 894-903; 2015. 

  5.  Andersen LP, Nielsen X: Methicillin-resistant Staphylococcus aureus transmission: unrecognised patient MRSA carriage. Dan. Med. J. 62:A5047; 2015

  6. Andersen PH: Opdaterede anbefalinger for malariaprofylakse. (Referencegruppen). EPI-nyt 2015; uge 26.

  7. Andersen SB, Marvig RL, Molin S, Johansen HK, Griffin AS: Long-term social dynamics drive loss of function in pathogenic bacteria. Proc. Natl. Acad. Sci. 112:10756-61; 2015

  8. Astvad K, Johansen HK, Høiby N, Steptoe P, Ishøy T: Oropharyngeal Candidiasis in Palliative Care Patients in Denmark. J. Palliat. Med. 18:940-4; 2015

  9. Aanaes K, Eickhardt S, Johansen HK, von Buchwald C, Skov M, Pressler T, Høiby N, Bjarnsholt T: Sinus biofilms in patients with cystic fibrosis — is adjusted eradication therapy needed? Eur. Arch. Otorhinolaryngol. 272:2291-7; 2015

  10. Bartels MD, Larner-Svensson H, Meiniche H, Kristoffersen K, Schonning K, Nielsen JB, Rohde SM, Christensen LB, Skibsted AW, Jarlov JO, Johansen HK, Andersen LP, Petersen IS, Crook DW, Bowden R, Boye K, Worning P, Westh H: Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing. Euro. Surveill. 20: sidetal?; 2015

  11. Bjarnsholt T, Alhede M, Jensen PØ, Nielsen AK, Johansen HK, Homøe P, Høiby N, Givskov M, Kirketerp-Møller K: Acetic acid completely eradicates bacterial biofilms: Adv. Wound Care (New Rochelle). 4:363-72; 2015.

  12. Bongard E, Frimodt-Møller N, Gal M, Wootton M, Howe R, Francis N, Goossens H, Butler CC: Analytic laboratory performance of a point of care urine culture kit for diagnosis and antibiotic susceptibility testing. Eur. J. Clin. Microbiol. Infect. Dis. 34:2111-9; 2015

  13.  Cao B, Christophersen L, Thomsen K, Sønderholm M, Bjarnsholt T, Jensen PØ, Høiby N, Moser C: Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model. J. Antimicr. Chemother. 70:2057-63; 2015.

  14. Chen M, Zhai L, Arendrup MC: In vitro activity of twenty-three tea extractions and epigallocatechin gallate against Candida species. Med. Mycol. 53:194-8; 2015

  15. Ciofu O, Tolker-Nielsen T, Jensen PØ, Wang H, Høiby N: Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients. Adv. Drug Deliv. Rev. 85:7-23; 2015

  16. Crone S, Garde C, Bjarnsholt T, Alhede M: A novel in vitro wound biofilm model used to evaluate low-frequency ultrasonic-assisted wound debridement. J. Wound Care. 24:64, 66-9; 2015

  17. Dayie NT, Arhin RE, Newman MJ, Dalsgaard A, Bisgaard M, Frimodt-Møller N: Slotved HC Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. Microb. Drug Resist. 21:636-42; 2015

  18. Efunshile A, Ngwu B, Kurtzhals JAL, Sahar S, König B, Stensvold CR: Molecular detection of the carriage rate of four intestinal protozoa with Real-Time PCR—possible overdiagnosis of Entamoeba histolytica in Nigeria. Am. J. Trop. Med. Hyg. 93:257-62; 2015

  19. Efunshile A, Olawale T, Stensvold C, Kurtzhals JAL, König B: Epidemiological study of the association between malaria and helminth infections in Nigeria. Am. J. Trop. Med. Hyg. 92:578-82; 2015

  20. Eickhardt S, Kragh KN, Schrøder S, Poulsen SS, Sillesen H, Givskov M, Høiby N, Bjarnsholt T, Alhede M: Autofluorescence in samples obtained from chronic biofilm infections--"all that glitters is not gold". Pathog. Dis. 73: sidetal?; 2015

  21. Frandsen TH, Albarazi C, Andersen LP: Simple method for routine detection of Legionella spp. in tap water. The battle against microbial pathogens: Basic science, technical advances and educational program. Ed. Méndes-Vilas A. 1078-83; 2015.

  22. Frimodt-Møller N, Bjerrum L: Kontroldyrkning efter behandling af urinvejsinfektion hos børn: Skal - skal ikke? Ugeskr. Laeger. 177:V67265; 2015

  23. Følsgaard NV, Nygaard U, Christiansen CB, Harder KM, Andersen PH, Poulsen A: Post-exposure prophylaxis against measles. Ugeskr. Laeger. 177:V06150467; 2015

  24. Ghoul M, West SA, Johansen HK, Molin S, Harrison OB, Maiden MC, Jelsbak L, Bruce JB, Griffin AS: Bacteriocin-mediated competition in cystic fibrosis lung infections. Proc. Biol. Sci. 282: sidetal?; 2015

  25. Hansson HH, Maretty L, Balle C, Goka BQ, Luzon E, Nkrumah FN, Schousboe ML, Rodrigues OP, Bygbjerg IC, Kurtzhals JA, Alifrangis M, Hempel C: Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children. Malar. J. 14:153; 2015.

  26. Hempel C, Boisen IM, Efunshile A, Kurtzhals JAL, Staalsø T: An automated method for determining the cytoadhesion of Plasmodium falciparum-infected erythrocytes to immobilized cells. Malar. J. 14:12; 2015

  27. Høiby N: Hvordan kan udvikling af resistens hos bakterier forhindres i almen praksis? BestPractice. Sygeplejersken I Almen Praksis 4:46-9; 2015.

  28. Høiby N, Bjarnsholt T, Moser C, Bassi GL, Coenye T, Donelli G, Hall-Stoodley L, Holá V, Imbert C, Kirketerp-Møller K, Lebeaux D, Oliver A, Ullmann AJ and Williams C for the ESCMID Study Group for Biofilms (ESGB) and consulting external expert Zimmerli W: ESCMID* guideline for the diagnosis and treatment of biofilm infections 2014. Clin. Microbiol. Infect. 21, Suppl.1:1-26; 2015

  29. Høiby N, Ciofu O, Bjarnsholt T: Pseudomonas. Chapter 42, ASM Manual of Clinical Microbiology, 11.ed.:773-90; 2015

  30. Høiby N, Ciofu O, Johansen HK, Andersen LP, Kemp M: Generel bakteriologi. Kompendium i Klinisk Mikrobiologi og Infektionsmedicin. Eds.Høiby N, Skinhøj P. FADL's forlag 1st eds. 35-130; 2015

  31. Høiby N, Johansen HK, Andersen LP, Kemp M: Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling. Kompendium i Klinisk Mikrobiologi og Infektionsmedicin. Eds Høiby N, Skinhøj P. FADL's forlag 1st eds. 245-338; 2015

  32. Høiby N, Skinhøj P (red.): Kompendium i mikrobiologi og infektionsmedicin. FADL's Forlag p. 1-338; 2015

  33. Ibfelt T, Engelund EH, Permin A, Madsen JS, Schultz AC, Andersen LP: Presence of Pathogenic Bacteria and Viruses in the Daycare Environment. J. Environ. Health. 78:24-9; 2015

  34. Ibfelt T, Engelund EH, Schultz AC, Andersen LP: Effect of cleaning and disinfection of toys on infectious diseases and micro-organisms in daycare nurseries. J. Hosp. Infect. 89:109-15; 2015

  35. Jahnsen RO, Sandberg-Schaal A, Frimodt-Møller N, Nielsen HM, Franzyk H: End group modification: Efficient tool for improving activity of antimicrobial peptide analogues towards Gram-positive bacteria. Eur. J. Pharm. Biopharm. 95:40-6; 2015

  36. Jensen A, Valdórsson O, Frimodt-Møller N, Hollingshead S, Kilian M: Commensal streptococci serve as a reservoir for β-lactam resistance genes in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 59:3529-40; 2015

  37. Jensen LK, Jensen HE, Koch J, Bjarnsholt T, Eickhardt S, Shirtliff M: Specific Antibodies to Staphylococcus aureus Biofilm Are Present in Serum from Pigs with Osteomyelitis. In Vivo. 29:555-60; 2015

  38. Joensen O, Paff T, Haarman EG, Skovgaard IM, Jensen PØ, Bjarnsholt T, Nielsen KG: Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections. PLoS One. 26;9:e115584; 2015

  39. Jørgensen KM: Adaptive mechanisms of P. aeruginosa during the chronic airways infection in patients with cystic fibrosis. Ph.d. afhandling. SUND, Københavns Universitet d. 2. oktober 2015

  40. Jørgensen KM, Wassermann T, Johansen HK, Christiansen LE, Molin S, Høiby N, Ciofu O: Diversity of metabolic prophiles of cystic fibrosis P. aeruginosa during the early stages of chronic lung infection. Microbiology 161:1447-62; 2015

  41. Kolpen M, Appeldorff CF, Brandt S, Mousavi N, Kragh KN, Aydogan S, Uppal HA, Bjarnsholt T, Ciofu O, Høiby N, Jensen PØ: Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions. Pathog. Dis. 74: sidetal?; 2015

  42. Kragh KN: Aspects of non-attached biofilm aggregates". Ph.d. afhandling. SUND, Københavns Universitet d. 15. december 2015

  43. Kolpen M, Kragh KN, Bjarnsholt T, Line L, Hansen CR, Dalbøge CD, Hansen N, Kühl M, Høiby N, Jensen PØ: Denitrification by cystic fibrosis pathogens – Stenotrophomonas maltophilia is dormant in sputum. Int. J. Med. Microbiol. 305:1-10; 2015

  44. Kruse AY, Kvich L, Eickhardt S, Omland LH, Bjarnsholt T, Moser C: Unexpected Diagnosis of Cerebral Toxoplasmosis by 16S and D2 Large-Subunit Ribosomal DNA PCR and Sequencing. J. Clin. Microbiol. 53:1983-5; 2015

  45. Larsen CS, Thybo S, Kurtzhals J, Møller NE, Vestergaard LS, Gade P, Andersen PH, Christiansen AH: Vaccinationsforslag ved udlandsrejse. EPI-nyt uge 27A+B; 2015

  46. Lauridsen RK, Rindzevicius T, Molin S, Johansen HK, Berg RW, Alstrøm TS, Almdal K, Larsen F, Schmidt MS, Boisen A: Towards quantitative SERS detection of hydrogen cyanide at ppb level for human breath analysis. Sensing and Biosensing Res. 5:84-9; 2015

  47. Lerche CJ, Christophersen LJ, Trøstrup H, Thomsen K,  Jensen PØ, Hougen HP, Bundgaard H, Høiby N, Moser C: Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis. Eur. J. Clin. Microbiol. Infect. Dis. 34:2349-57; 2015

  48. 48.   Liu X, Frydenvang K, Liu H, Zhai L, Chen M, Olsen CE, Brøgger S, Christensen SB: Iminolactones from Schizophyllum commune. J. Nat. Prod. 78:5:1165-8; 2015

  49. Madsen AF: Oplevelse af isolation under indlæggelse – Et kvalitativt studie". Masterafhandling. Nordic School of Public Health, Gøteborg den 11. december 2014

  50. Marvig RL, Dolce D, Sommer LM, Petersen B, Ciofu O, Campana S, Molin S, Taccetti G, Johansen HK: Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients. BMC Microbiology 15:218; 2015

  51. Marvig RL, Sommer LM, Jelsbak L, Molin S, Johansen HK: Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients. Future Microbiol. 10:599-611; 2015

  52. 52.   Marvig RL, Sommer LM, Molin S, Johansen HK: Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis. Nat. Genet. 47:57-64; 2015.
  53. Midgley SE, Christiansen CB, Poulsen MW, Hansen CH, Fischer TK: Emergence of enterovirus D68 in Denmark, June 2014 to February 2015. Euro. Surveill. 20pii 21105; 2015

  54. Miller WG, Yee E, On SL, Andersen LP, Bono JL: Complete Genome Sequence of the Campylobacter ureolyticus Clinical Isolate RIGS 9880. Genome Announc. 3; 2015

  55. Oddo A, Nyberg NT, Frimodt-Møller N, Thulstrup PW, Hansen PR: The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide. Eur. J. Med. Chem. 102:574-81; 2015

  56. Oddo A, Thomsen TT, Kjelstrup S, Gorey C, Franzyk H, Frimodt-Møller N, Løbner-Olesen A, Hansen PR: An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action. Antimicrob. Agents Chemother. 60:592-9; 2015

  57. Olesen UK, Juul R, Bonde CT, Moser C, McNally M, Jensen LT, Elberg JJ, Eckardt H: Optimal timing of soft tissue cover and choice of antibiotic therapy in the prevention of complications in open tibial fractures. Int. Orthopedics 39:1159-66; 2015

  58. Paulsson M, Singh B, Al-Jubair T, Su Y-C, Høiby N, Riesbeck C: Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa. J. Cyst. Fibros. 14:600-7; 2015

  59. Pinholt M, Larner-Svensson H, Littauer PJ, Moser C, Pedersen M, Lemming LE, Ejlertsen T, Søndergaard TS, Holzknecht BJ, Justesen US, Dzajic E, Olsen SS, Nielsen JB, Worning P, Hammerum AM, Westh H, Jakobsen L: Multiple hospital outbreaks of vanA Enterococcus faecium in Denmark, 2012-2013 investigated by WGS, MLST and PFGE. J. Antimicrob. Chemother. 70: 2474-82; 2015

  60. Poelman R, Schuffenecker I, van Leer-Buter C, Josset L, Niesters HG, Lina B: ESCV-ECDC EV-D68 study group. J. Clin. Virol. 71:1-9; 2015

  61. Prahl JB, Johansen IS, Cohen AS, Frimodt-Møller N, Andersen ÅB: Clinical significance of 2 h plasma concentrations of first-line anti-tuberculosis drugs: a prospective observational study--authors' response. J. Antimicrob. Chemother. 70:321-2; 2015

  62. Pulcini C, Wencker F, Frimodt-Møller N, Kern WV, Nathwani D, Rodríguez-Baño J, Simonsen GS, Vlahović-Palčevski V, Gyssens IC; ESGAP Curriculum Working Group: European survey on principles of prudent antibiotic prescribing teaching in undergraduate students. Clin. Microbiol. Infect. 21:354-61; 2015

  63. Quist T: Nontuberculous mycobacteria among patients with cystic fibrosis. Ph.d. afhandling. Rigshospitalet d. 15. juni 2015

  64. Quist T, Giljam M, Jönsson B, Taylor-Robinson D, Jensen-Fangel S, Wang M, Svahn A, Kötz K, Hansson L, Hollsing A, Hansen CR, Finstad PL, Høiby N, Katzenstein TL: Epidemiology of nontuberculous mycobacteria among patients with cystic fibrosis in Scandinavia. J. Cyst. Fibros. 14:46-52; 2015

  65. Qvist T, Pressler T, Taylor-Robinson D, Katzenstein TL, Høiby N: Serodiagnosis of  Mycobacterium abscessus complex infection in cystic fibrosis. Eur. Respir. J. 46:707-16; 2015 

  66. Rasmussen MM, Opintan JA, Frimodt-Møller N, Styrishave B: Beta-Lactamase Producing Escherichia coli Isolates in Imported and Locally Produced Chicken Meat from Ghana. PLoS One. 10:e0139706; 2015

  67. Roberts AE, Kragh KN, Bjarnsholt T, Diggle SP: The Limitations of In Vitro Experimentation in Understanding Biofilms and Chronic Infection. J. Mol. Biol. 427:3646-61; 2015

  68. Rybtke M, Berthelsen J, Yang L, Høiby N, Givskov M, Tolker-Nielsen T: The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesion on the cell surface. MicrobiolologyOpen 4:917-30; 2015

  69. Sánchez-Céspedes J, Sáez-López E, Frimodt-Møller N, Vila J, Soto SM: Effects of a Mutation in the gyrA Gene on the Virulence of Uropathogenic Escherichia coli. Antimicrob. Agents Chemother. 59:4662-8; 2015

  70. Skindersoe ME, Rasmussen L, Andersen LP, Krogfelt KA: A Novel Assay for Easy and Rapid Quantification of Helicobacter pylori Adhesion. Helicobacter. 20:199-205; 2015

  71. Skov M, Pressler T, Lykkesfeldt J, Poulsen HE, Jensen PØ, Johansen HK, Qvist T, Kræmer D, Høiby N, Ciofu O: The effect of short-term, high-dose oral N-acetylcystein treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection – A pilot study. J. Cyst. Fibros. 14:211-8; 2015

  72. Sparding N, Dayie NT, Mills RO, Newman MJ, Dalsgaard A, Frimodt-Møller N, Slotved HC: Clonal distribution of pneumococcal serotype 19F isolates from Ghana. Infect. Genet. Evol. 31:68-72; 2015

  73. Theander TG, Kurtzhals JAL: Parasitologi. Kompendium i Klinisk Mikrobiologi og Infektionsmedicin. Eds.Høiby N, Skinhøj P. FADL's forlag 1st eds.; 2015.

  74. Thomsen K, Christophersen L, Bjarnsholt T, Jensen PØ, Moser C, Høiby N: Anti-Pseudomonas aeruginosa IgY antibodies induce specific bacterial aggregation and internalization in human polymorphonuclear neutrophils. Infect. Immun. 83:2686-93; 2015

  75. Topp SK, Rosenfeldt V, Vestergaard H, Christiansen CB, von Linstow ML: Clinical characteristics and laboratory findings in Danish children hospitalized with primary Epstein-Barr virus infection. Infect. Dis. 47:908-14; 2015

  76. Uggerhøj LE, Poulsen TJ, Munk JK, Fredborg M, Sondergaard TE, Frimodt-Moller N, Hansen PR, Wimmer R: Rational design of alpha-helical antimicrobial peptides: do's and don'ts. Chembiochem. 16:242-53; 2015

  77. Uhlving HH, Andersen CB, Christensen IJ, Gormsen M, Pedersen KD, Buchvald F, Heilmann C, Nielsen KG, Mortensen J, Moser C, Sengeløv H, Müller KG: Biopsy-Verified Bronchiolitis Obliterans in Allogenic Haematopoietic Stem Cell Transplantation. Biol. Blood Marrow Transplant. 21:531-8; 2015

  78. Walduck A, Andersen LP, Raghaven S: Inflammation, Immunity and Vaccines for Helicobacter pylori infection. Helicobacter. Suppl 1:17-25; 2015

  79. Wang H, Jørgensen C, Ciofu O, Christophersen L, Kolpen M, Jensen PØ, Song Z, Moser C, Høiby N:  Pharmacodynamics of ceftazidime combined with β-lactamase inhibitor in biofilm P. aeruginosa in vitro. J. Cyst. Fibros. 14:suppl. 1:4; 2015

  80. Wu H, Moser C, Wang H, Høiby N, Song Z: Strategies for combating bacterial biofilm infections. Int. J. Oral Sci. 7:1-7; 2015 (2014, on-line: doi:10.1038/ijos.2014.65)

  81. Aanaes K, Eickhardt S, Johansen HK, von Buchwald C, Skov M, Høiby N, Bjarnsholt T: Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed? Eur. Arch. Otorhinolaryngol. 272:2291-7; 2015.