​OxyPrem is a Near-Infrared-Spectroscopy (NIRS) device which is developed particularly for application in Neonatology to measure brain oxygenation in the framework of the SafeBoosC study.

OxyPrem is a reusable sensor with comparably small source-detector distances of 1.5 and 2.5 cm which have been determined optimal for neonates [1] and reduce light output and power dissipation. OxyPrem implements the self-calibrating principle [2] for superior precision [3].

OxyPrem was developed at the Biomedical Optics Research Laboratory at the Division of Neonatology at the University Hospital Zurich, Switzerland. For further Information please contact oxyprem@usz.ch.

[1] Greisen, G., T. Leung, et al. (2011). "Has the time come to use near-infrared spectroscopy as a routine clinical tool in preterm infants undergoing intensive care?" Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences 369(1955): 4440-4451.

[2] Hueber, D. M., S. Fantini, et al. (1999). "New optical probe designs for absolute (self-calibrating) NIR tissue hemoglobin measurements." Optical Tomography and Spectroscopy of Tissue III Proc. SPIE 3597: 618-631.

[3] Jenny, C., M. Biallas, et al. (2011). "Reproducibility of cerebral tissue oxygen saturation measurements by near-infrared spectroscopy in newborn infants." Journal of Biomedical Optics 16(9): 097004.