We perform studies on patients with rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and other inflammatory arthritides.
The studies are performed in collaboration with Danish and/or international researchers and pharmaceutical companies.
The DANBIO database is one of the largest observational registries in rheumatology in the world. The database collects information about “ordinary” arthritis patients undergoing treatment in routine care. In 2015, we further established the nationwide biobank, Danish Rheumatology Biobank. The two sources of data combined have resulted in an optimal environment for current and future research projects. Both DANBIO and Danish Rheumatology Biobank are frequently used for national clinical and epidemiological research. We also collaborate with other European countries via the EULAR organization, in which context the high qualitity data has also proven valuable.
As exemplified with the Danish Rheumatology Biobank, we have extensive experience with establishing biobanks in association with our clinical studies.
We use these to search for soluble biomarkers that can predict disease course and treatment outcome, thus paving the way for personalized medicine.
Danish Rheumatology Biobank was established in collaboration with leading rheumatologists across Denmark and is funded by the Danish Regions and the Danish Arthritis Association. The chairmanship of the scientific committee of DRB lies within COPECARE.
We have strong expertise in performing methodological and clinical ultrasound studies
- Synovitis according to the EULAR/OMERACT semi-quantitative scoring system and quantitative spectral Doppler, and with a pixel calculation software
- Tenosynovitis and enthesitis according to the EULAR/OMERACT semi-quantitative scoring system.
We have extensive national and international teaching experience in ultrasound, and participate in the development and implementation of internationally agreed ultrasound competency assessments such as those recommended by EFSUMB and EULAR.
Magnetic resonance imaging
We have strong expertise in performing methodological and clinical studies with magnetic resonance imaging (MRI).
With other researchers, we have developed and validated methods to evaluate MR images, e.g.:
- The Rheumatoid Arthritis MRI Score (RAMRIS)
- The Psoriatic Arthritis MRI Score (PsAMRIS)
- The OMERACT Joint Space Narrowing score
- The CanDen MRI definitions for axial spondyloarthritis
- The Fat Spondyloarthritis Spine Score (FASSS)
- The SPARCC Sacroiliac Joint Structural Score
We have expertise in evaluation of MR images according to all of these methods., and also according to:
- The Spondyloarthritis Research Consortium of Canada (SPARCC) Spine Inflammation Index
- The SPARCC Sacroiliac Joint Inflammation Index
- We also have extensive national and international teaching experience in magnetic resonance imaging of inflammatory arthritides.
We have expertise in evaluation of radiographs according to established scoring methods such as:
- The Sharp van der Heijde score
- The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS)
- The modified New York Criteria for Ankylosing Spondylitis