Toppublikationer

Reduction in Acute Limb Ischemia with Rivaroxaban versus Placebo in Peripheral Artery Disease after Lower Extremity Revascularization: Insights from VOYAGER PAD (Circulation)

Address the Foreskin in Newborn Boys with Posterior Urethral Valves, in One Way or Another! (European urology)

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (Intensive care medicine)

Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial (JAMA)

Association of Labor Epidural Analgesia With Autism Spectrum Disorder in Children (JAMA)

Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial (Nature medicine)

Paracetamol use during pregnancy - a call for precautionary action (Nature reviews. Endocrinology)

Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP (Nature reviews. Neurology)

DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia (Leukemia)

Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study (Lancet (London, England))

The growing field of digital psychiatry: current evidence and the future of apps, social media, chatbots, and virtual reality (World psychiatry : official journal of the World Psychiatric Association (WPA))

Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study (PLoS medicine)

Incidence of ischaemic stroke and mortality in patients with acute coronary syndrome and first-time detected atrial fibrillation: a nationwide study (European heart journal)

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society (European heart journal)

Day-to-day measurement of physical activity and risk of atrial fibrillation (European heart journal)

Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial (Lancet (London, England))

Response by Hasselbalch et al to Letter Regarding Article, "Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans" (Circulation)

Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation (The New England journal of medicine)

Effect of Empagliflozin on Worsening Heart Failure Events in Patients With Heart Failure and Preserved Ejection Fraction: EMPEROR-Preserved Trial (Circulation)

Influenza Vaccination after Myocardial Infarction: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial (Circulation)

Effect of dapagliflozin on ventricular arrhythmias, resuscitated cardiac arrest, or sudden death in DAPA-HF (European heart journal)

Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications (Brain : a journal of neurology)

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials (The lancet. Diabetes & endocrinology)

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum (Acta neuropathologica)

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest (Intensive care medicine)

Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study (Annals of the rheumatic diseases)

Effectiveness of Adding a Mask Recommendation to Other Public Health Measures (Annals of internal medicine)

Endothelial dysfunction and thromboembolism in children, adolescents, and young adults with acute lymphoblastic leukemia (Leukemia)

Association of Variants Near the Bradykinin Receptor B₂ Gene With Angioedema in Patients Taking ACE Inhibitors (Journal of the American College of Cardiology)

Effect of Rivaroxaban and Aspirin in Patients With Peripheral Artery Disease Undergoing Surgical Revascularization: Insights From the VOYAGER PAD Trial (Circulation)

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis (Intensive care medicine)

Is oropharyngeal sampling a reliable test to detect SARS-CoV-2? (The Lancet. Infectious diseases)

Multicenter Study of Endocarditis After Transcatheter Pulmonary Valve Replacement (Journal of the American College of Cardiology)

Variant PNLDC1, Defective piRNA Processing, and Azoospermia (The New England journal of medicine)

Genome-wide association study identifies 18 novel loci associated with left atrial volume and function (European heart journal)

False hope for patients with Klinefelter syndrome on cryopreservation of spermatogonia at younger ages (Human reproduction update)

Vaginal estrogen and association with dementia: A nationwide population-based study (Alzheimer's & dementia : the journal of the Alzheimer's Association)

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores (Journal of the National Cancer Institute)

Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy (European heart journal)

Association of Cycling With All-Cause and Cardiovascular Disease Mortality Among Persons With Diabetes: The European Prospective Investigation Into Cancer and Nutrition (EPIC) Study (JAMA internal medicine)

The Modulatory Role of Serotonin on Human Impulsive Aggression (Biological psychiatry)

Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections (The Journal of clinical investigation)

Oral fluoroquinolones and risk of aortic or mitral regurgitation: a nationwide nested case-control study (European heart journal)

Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma: a study of younger patients from the MCL2 and MCL3 clinical trials (Leukemia)

HIV infection is associated with thoracic and abdominal aortic aneurysms: a prospective matched cohort study (European heart journal)

Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium (Blood)

Paternity After Treatment for Testicular Germ Cell Cancer: A Danish Nationwide Population-Based Cohort Study (Journal of the National Cancer Institute)

Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement (European heart journal)

DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis (Leukemia)

RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis (Molecular cell)

Separating parental and treatment contributions to perinatal health after fresh and frozen embryo transfer in assisted reproduction: A cohort study with within-sibship analysis (PLoS medicine)

Parenthood Rates and Use of Assisted Reproductive Techniques in Younger Hodgkin Lymphoma Survivors: A Danish Population-Based Study (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations (Leukemia)

Around the clock, around the world-reflections on 24 hours of acute cardiovascular care (European heart journal)

Diagnosis and management of migraine in ten steps (Nature reviews. Neurology)

2021 MAGNIMS-CMSC-NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis (The Lancet. Neurology)

Anterior uveitis in patients with spondyloarthritis treated with secukinumab or tumour necrosis factor inhibitors in routine care: does the choice of biological therapy matter? (Annals of the rheumatic diseases)

Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1) (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Final Overall Survival Analysis of the TOURMALINE-MM1 Phase III Trial of Ixazomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Therapeutic options for CTLA-4 insufficiency (The Journal of allergy and clinical immunology)

Twice-daily chemoradiotherapy in limited-stage small-cell lung cancer - Authors' reply (The Lancet. Oncology)

Radiation Dose Escalation for Early Prostate Cancer: Reigniting the FLAME? (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Effectiveness and treatment retention of TNF inhibitors when used as monotherapy versus comedication with csDMARDs in 15 332 patients with psoriatic arthritis. Data from the EuroSpA collaboration (Annals of the rheumatic diseases)

Metabolic Effects of Empagliflozin in Heart Failure: A Randomized, Double-Blind, and Placebo-Controlled Trial (Empire HF Metabolic) (Circulation)

Time for tocilizumab in COVID-19? (Intensive care medicine)

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis (Cell)

Colorectal cancer screening in Europe: what are the next steps? (The Lancet. Oncology)

EULAR recommendations for intra-articular therapies (Annals of the rheumatic diseases)

Atrial Fibrillation and Chronic Kidney Disease (European heart journal)

Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment (The Lancet. Neurology)

Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities (The Lancet. Infectious diseases)

Targeting IL-6 in patients at high cardiovascular risk (Lancet (London, England))

The European bifurcation club Left Main Coronary Stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN) (European heart journal)

2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis (Annals of the rheumatic diseases)

Permanent Pacemaker Implantation Following Valve-in-Valve Transcatheter Aortic Valve Replacement: VIVID Registry (Journal of the American College of Cardiology)

A systematic review and meta-analysis on the association between ICSI and chromosome abnormalities (Human reproduction update)

Driving following defibrillator implantation: a nationwide register-linked survey study (European heart journal)

Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study (BMJ (Clinical research ed.))

Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution (Cancer discovery)

Comparative effectiveness of two adalimumab biosimilars in 1318 real-world patients with inflammatory rheumatic disease mandated to switch from originator adalimumab: nationwide observational study emulating a randomised clinical trial (Annals of the rheumatic diseases)

ST-Segment Elevation Myocardial Infarction Following Transcatheter Aortic Valve Replacement (Journal of the American College of Cardiology)

Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1 (Acta neuropathologica)

Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis (Intensive care medicine)

Real-World Effectiveness of Human Papillomavirus Vaccination Against Cervical Cancer (Journal of the National Cancer Institute)

Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy (Circulation)

Fluid volume regulation in patients with heart failure - Authors' reply (The lancet. Diabetes & endocrinology)

Effect of Early Recombinant Human Erythropoietin on Neurodevelopmental Outcomes at Age 5 Years (JAMA)

Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study (The Lancet. Oncology)

Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus (Journal of the American College of Cardiology)

Dapagliflozin and Recurrent Heart Failure Hospitalizations in Heart Failure With Reduced Ejection Fraction: An Analysis of DAPA-HF (Circulation)

Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Maternal weight change from prepregnancy to 18 months postpartum and subsequent risk of hypertension and cardiovascular disease in Danish women: A cohort study (PLoS medicine)

Replication study of plasma proteins relating to Alzheimer's pathology (Alzheimer's & dementia : the journal of the Alzheimer's Association)

Migraine: epidemiology and systems of care (Lancet (London, England))

Migraine: integrated approaches to clinical management and emerging treatments (Lancet (London, England))

Migraine: disease characterisation, biomarkers, and precision medicine (Lancet (London, England))

Opening of ATP sensitive potassium channels causes migraine attacks with aura (Brain : a journal of neurology)

Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus (Annals of the rheumatic diseases)

Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior" (Science (New York, N.Y.))

Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial): A Double-Blinded, Placebo-Controlled, Single-Center, Randomized, Clinical Trial (Circulation)