Toppublikationer

Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis (Biological psychiatry)

Pomalidomide, bortezomib, and dexamethasone for multiple myeloma previously treated with lenalidomide (OPTIMISMM): outcomes by prior treatment at first relapse (Leukemia)

Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial (The Lancet. Oncology)

A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes (Cell metabolism)

rs641738C>T near MBOAT7 is associated with liver fat, ALT, and fibrosis in NAFLD: a meta-analysis (Journal of hepatology)

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis (JAMA)

New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy (Brain : a journal of neurology)

Use of Hydrocortisone Based on Plasma Biomarkers in Patients with Septic Shock: Another One Bites the Dust? (American journal of respiratory and critical care medicine)

The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial (European heart journal)

Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement (Journal of the American College of Cardiology)

Who would have thought - myokines two decades on (Nature reviews. Endocrinology)

Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: an updated systematic review and network meta-analysis of randomized trials (Intensive care medicine)

Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia (The Lancet. Neurology)

MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF) (European heart journal)

Dabrafenib plus trametinib in patients with BRAF^V600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial (The Lancet. Oncology)

Performance of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in early disease, across sexes and ethnicities (Annals of the rheumatic diseases)

A Phase 2a, Double-Blind, Placebo-Controlled Randomized Trial of Inhaled TLR9 Agonist AZD1419 in Asthma (American journal of respiratory and critical care medicine)

APOE and dementia - resequencing and genotyping in 105,597 individuals (Alzheimer's & dementia : the journal of the Alzheimer's Association)

Fluid trials: searching for a solution to an age-old problem (Intensive care medicine)

Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Long-Term Adverse Cardiac Outcomes in Patients With Sarcoidosis (Journal of the American College of Cardiology)

Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report (Annals of internal medicine)

Letter by Helgestad et al Regarding Article, "The Evolving Landscape of Impella Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support" (Circulation)

Expanding our understanding of ovarian cancer risk: the role of incomplete pregnancies (Journal of the National Cancer Institute)

Freeze-all versus fresh blastocyst transfer strategy during in vitro fertilisation in women with regular menstrual cycles: multicentre randomised controlled trial (BMJ (Clinical research ed.))

Risk of COVID-19 in health-care workers in Denmark: an observational cohort study (The Lancet. Infectious diseases)

The Impact of Coronavirus Disease 2019 (COVID-19) on First-time Acute Stroke and Transient Ischemic Attack Admission Rates and Prognosis in Denmark: A Nationwide Cohort Study (Circulation)

De Novo and Bi-allelic Pathogenic Variants in NARS1 Cause Neurodevelopmental Delay Due to Toxic Gain-of-Function and Partial Loss-of-Function Effects (American journal of human genetics)

Rituximab-CHOP With Early Rituximab Intensification for Diffuse Large B-Cell Lymphoma: A Randomized Phase III Trial of the HOVON and the Nordic Lymphoma Group (HOVON-84) (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Correction: Epidemiology of bloodstream infections in patients with chronic lymphocytic leukemia: a longitudinal nation-wide cohort study (Leukemia)

The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history (Brain : a journal of neurology)

Second-line and Third-line therapy for Autoimmune Hepatitis A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group (Journal of hepatology)

Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease (European heart journal)

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome (Blood)

Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump for Cardiogenic Shock (JAMA)

Antimicrobial use before chronic lymphocytic leukemia: a retrospective cohort study (Leukemia)

Meta-analysis of the Glial Marker TSPO in Psychosis Revisited: Reconciling Inconclusive Findings of Patient-Control Differences (Biological psychiatry)

Health-related quality of life in survivors of septic shock: 6-month follow-up from the ADRENAL trial (Intensive care medicine)

Dapagliflozin and Diuretic Use in Patients With Heart Failure and Reduced Ejection Fraction in DAPA-HF (Circulation)

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus (Leukemia)

A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement. Reply (The New England journal of medicine)

Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy (Leukemia)

Smartphone Activation of Citizen Responders to Facilitate Defibrillation in Out-of-Hospital Cardiac Arrest (Journal of the American College of Cardiology)

New approaches to cancer care in a COVID-19 world (The Lancet. Oncology)

Sirolimus with CSP and MMF as GVHD prophylaxis for allogeneic transplantation with HLA antigen mismatched donors (Blood)

COVID-19 among fit patients with CLL treated with venetoclax-based combinations (Leukemia)

Long-term outcomes after transcatheter aortic valve implantation in failed bioprosthetic valves (European heart journal)

Sodium and health-concordance and controversy (BMJ (Clinical research ed.))

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity (Cell metabolism)

Hydroxychloroquine shortages among patients with systemic lupus erythematosus during the COVID-19 pandemic: experience of the Systemic Lupus International Collaborating Clinics (Annals of the rheumatic diseases)

Mapping interventional cardiology in Europe: the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Atlas Project (European heart journal)

Prevalence of Infective Endocarditis in Streptococcal Bloodstream Infections Is Dependent on Streptococcal Species (Circulation)

New-onset atrial fibrillation: incidence, characteristics, and related events following a national COVID-19 lockdown of 5.6 million people (European heart journal)

Tranexamic acid for severe gastrointestinal bleeding (Lancet (London, England))

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality (JAMA)

Long-term Consequences of Undiagnosed Celiac Seropositivity (The American journal of gastroenterology)

Management of cancer and health after the clinic visit: A call to action for self-management in cancer care (Journal of the National Cancer Institute)

How likely are COVID-19 interventions to benefit the sickest patients? (Intensive care medicine)

Managing ICU surge during the COVID-19 crisis: rapid guidelines (Intensive care medicine)

Performance of a guideline-recommended algorithm for prognostication of poor neurological outcome after cardiac arrest (Intensive care medicine)

Corrigendum to 'EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer-An International Collaborative Multistakeholder Effort Under the Auspices of the EAU-ESMO Guidelines Committees' [European Urology 77 (2020) 223-250] (European urology)

Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis (The lancet. Diabetes & endocrinology)

Remdesivir for the Treatment of Covid-19 - Preliminary Report (The New England journal of medicine)

Management of patients with multiple myeloma in the era of COVID-19 pandemic: a consensus paper from the European Myeloma Network (EMN) (Leukemia)

Cardiac natriuretic peptides (Nature reviews. Cardiology)

Response to: 'Neuroinflammatory events after anti-TNFα therapy' by Kaltsonoudis et al (Annals of the rheumatic diseases)

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis (Nature)

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome (Circulation)

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (Nature genetics)

Congestion in heart failure: a contemporary look at physiology, diagnosis and treatment (Nature reviews. Cardiology)

Compassionate Use of Remdesivir in Covid-19 (The New England journal of medicine)

Understanding necrotizing soft tissue infections in the intensive care unit (Intensive care medicine)

Muscle-Organ Crosstalk: The Emerging Roles of Myokines (Endocrine reviews)

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia (Blood)

Psoriatic arthritis: still room for improvement (Lancet (London, England))

When Should Clinicians Act on Non-Statistically Significant Results From Clinical Trials? (JAMA)

Efficacy and safety of azithromycin maintenance therapy in primary ciliary dyskinesia (BESTCILIA): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial (The Lancet. Respiratory medicine)

Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability (The Journal of clinical investigation)

Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study (European heart journal)

Central reader evaluation of MRI scans of the sacroiliac joints from the ASAS classification cohort: discrepancies with local readers and impact on the performance of the ASAS criteria (Annals of the rheumatic diseases)

TAS-102 plus bevacizumab in metastatic colorectal cancer - Authors' reply (The Lancet. Oncology)

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease (Nature genetics)

Focus on sepsis (Intensive care medicine)

Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dysfunction (Journal of the American College of Cardiology)

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia (Blood)

Focus on cardiovascular management in critically ill patients (Intensive care medicine)

Germline Elongator mutations in Sonic Hedgehog medulloblastoma (Nature)

Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs (The New England journal of medicine)

ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic (Blood)

Correction: Flow cytometric detection of leukemic blasts in cerebrospinal fluid predicts risk of relapse in childhood acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology study (Leukemia)

Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study (The American journal of psychiatry)

Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure (Circulation)

Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19) (Intensive care medicine)

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy (European heart journal)

Stage I-II nodular lymphocyte-predominant Hodgkin lymphoma: a multi-institutional study of adult patients by ILROG (Blood)

Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study (Leukemia)

Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population (Hepatology (Baltimore, Md.))

Reply to S.C. Clasen et al (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Clonal hematopoiesis evolves from pretreatment clones and stabilizes after end of chemotherapy in patients with MCL (Blood)