Toppublikationer

Anterior uveitis in patients with spondyloarthritis treated with secukinumab or tumour necrosis factor inhibitors in routine care: does the choice of biological therapy matter? (Annals of the rheumatic diseases)

Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1) (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Final Overall Survival Analysis of the TOURMALINE-MM1 Phase III Trial of Ixazomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Therapeutic options for CTLA-4 Insufficiency (The Journal of allergy and clinical immunology)

Twice-daily chemoradiotherapy in limited-stage small-cell lung cancer - Authors' reply (The Lancet. Oncology)

Radiation Dose Escalation for Early Prostate Cancer: Reigniting the FLAME? (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Effectiveness and treatment retention of TNF inhibitors when used as monotherapy versus comedication with csDMARDs in 15 332 patients with psoriatic arthritis. Data from the EuroSpA collaboration (Annals of the rheumatic diseases)

Metabolic Effects of Empagliflozin in Heart Failure: A Randomized, Double-Blind, and Placebo-Controlled Trial (Empire HF Metabolic) (Circulation)

Time for tocilizumab in COVID-19? (Intensive care medicine)

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis (Cell)

Colorectal cancer screening in Europe: what are the next steps? (The Lancet. Oncology)

EULAR recommendations for intra-articular therapies (Annals of the rheumatic diseases)

Atrial Fibrillation And Chronic Kidney Disease (European heart journal)

Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment (The Lancet. Neurology)

Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities (The Lancet. Infectious diseases)

Targeting IL-6 in patients at high cardiovascular risk (Lancet (London, England))

The European bifurcation club Left Main Coronary Stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN) (European heart journal)

2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis (Annals of the rheumatic diseases)

Permanent Pacemaker Implantation Following Valve-in-Valve Transcatheter Aortic Valve Replacement: VIVID Registry (Journal of the American College of Cardiology)

A systematic review and meta-analysis on the association between ICSI and chromosome abnormalities (Human reproduction update)

Driving following defibrillator implantation: a nationwide register-linked survey study (European heart journal)

Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study (BMJ (Clinical research ed.))

Comparative effectiveness of two adalimumab biosimilars in 1318 real-world patients with inflammatory rheumatic disease mandated to switch from originator adalimumab: nationwide observational study emulating a randomised clinical trial (Annals of the rheumatic diseases)

ST-Segment Elevation Myocardial Infarction Following Transcatheter Aortic Valve Replacement (Journal of the American College of Cardiology)

Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1 (Acta neuropathologica)

Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis (Intensive care medicine)

Real-world Effectiveness of Human Papillomavirus Vaccination Against Cervical Cancer (Journal of the National Cancer Institute)

Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy (Circulation)

Fluid volume regulation in patients with heart failure - Authors' reply (The lancet. Diabetes & endocrinology)

Effect of Early Recombinant Human Erythropoietin on Neurodevelopmental Outcomes at Age 5 Years (JAMA)

Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study (The Lancet. Oncology)

Long-Term Cardiovascular Outcomes in Systemic Lupus Erythematosus (Journal of the American College of Cardiology)

Dapagliflozin and Recurrent Heart Failure Hospitalizations in Heart Failure With Reduced Ejection Fraction: An Analysis of DAPA-HF (Circulation)

Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Maternal weight change from prepregnancy to 18 months postpartum and subsequent risk of hypertension and cardiovascular disease in Danish women: A cohort study (PLoS medicine)

Replication study of plasma proteins relating to Alzheimer's pathology (Alzheimer's & dementia : the journal of the Alzheimer's Association)

Migraine: epidemiology and systems of care (Lancet (London, England))

Migraine: integrated approaches to clinical management and emerging treatments (Lancet (London, England))

Migraine: disease characterisation, biomarkers, and precision medicine (Lancet (London, England))

Opening of ATP sensitive potassium channels causes migraine attacks with aura (Brain : a journal of neurology)

Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus (Annals of the rheumatic diseases)

Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior" (Science (New York, N.Y.))

Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial): A Double-Blinded, Placebo-Controlled, Single-Center, Randomized, Clinical Trial (Circulation)

Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell-Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Survival and New Prognosticators in Metastatic Seminoma: Results From the IGCCCG-Update Consortium (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Risk for Non-AIDS-Defining and AIDS-Defining Cancer of Early Versus Delayed Initiation of Antiretroviral Therapy : A Multinational Prospective Cohort Study (Annals of internal medicine)

Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia (Leukemia)

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma (Cancer cell)

Five-Year Outcomes of PFO Closure or Antiplatelet Therapy for Cryptogenic Stroke (The New England journal of medicine)

Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics (Pharmacological reviews)

Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency (Hepatology (Baltimore, Md.))

Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group (The Lancet. Oncology)

High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial (The Lancet. Oncology)

Response to: 'Correspondence on 'MRI lesions in the sacroiliac joints of patients with spondyloarthritis: an update of definitions and validation by the ASAS MRI working group'' by Jibri et al (Annals of the rheumatic diseases)

Prognostic Value of Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes (Journal of the American College of Cardiology)

All-cause mortality and location of death in patients with established cardiovascular disease before, during, and after the COVID-19 lockdown: a Danish Nationwide Cohort Study (European heart journal)

Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye (JAMA)

Placebo-The Unknown Variable in a Controlled Trial (JAMA internal medicine)

Mapping comorbidity in chronic lymphocytic leukemia: impact of individual comorbidities on treatment, mortality, and causes of death (Leukemia)

Reactive astrocyte nomenclature, definitions, and future directions (Nature neuroscience)

Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li-Fraumeni syndrome (Leukemia)

European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance (Annals of the rheumatic diseases)

Prevalence of Bicuspid Aortic Valve and Associated Aortopathy in Newborns in Copenhagen, Denmark (JAMA)

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer in the APHINITY Trial: 6 Years' Follow-Up (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Monoclonal Antibody for Patients with Covid-19. Reply (The New England journal of medicine)

European position paper on the management of patients with patent foramen ovale. Part II - Decompression sickness, migraine, arterial deoxygenation syndromes and select high-risk clinical conditions (European heart journal)

Psychiatric Medication Use After Possible Neuroborreliosis-Reply (JAMA psychiatry)

Identifying New Antimigraine Targets: Lessons from Molecular Biology (Trends in pharmacological sciences)

EULAR recommendations for the reporting of ultrasound studies in rheumatic and musculoskeletal diseases (RMDs) (Annals of the rheumatic diseases)

Coronary flow velocity reserve predicts adverse prognosis in women with angina and no obstructive coronary artery disease: results from the iPOWER study (European heart journal)

Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (Nature genetics)

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure (The New England journal of medicine)

Transcatheter Replacement of Transcatheter Versus Surgically Implanted Aortic Valve Bioprostheses (Journal of the American College of Cardiology)

Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (Nature genetics)

Real-world effectiveness of Human Papillomavirus vaccination against vulvovaginal high-grade precancerous lesions and cancers (Journal of the National Cancer Institute)

Impact of food supplements on early child development in children with moderate acute malnutrition: A randomised 2 x 2 x 3 factorial trial in Burkina Faso (PLoS medicine)

Effects of empagliflozin on estimated extracellular volume, estimated plasma volume, and measured glomerular filtration rate in patients with heart failure (Empire HF Renal): a prespecified substudy of a double-blind, randomised, placebo-controlled trial (The lancet. Diabetes & endocrinology)

Defining the Optimal Total Number of Chemotherapy Courses in Younger Patients With Acute Myeloid Leukemia: A Comparison of Three Versus Four Courses (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19 (The New England journal of medicine)

Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)

Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting (Leukemia)

Temporal Changes in Secondary Prevention and Cardiovascular Outcomes After Revascularization for Peripheral Arterial Disease in Denmark: A Nationwide Cohort Study (Circulation)

Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy (Leukemia)

Association between conflicts of interest and favourable recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews: systematic review (BMJ (Clinical research ed.))

Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans (Circulation)

The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study (European heart journal)

Bipolar disorders (Lancet (London, England))

Performance and operational feasibility of two diagnostic tests for cryptosporidiosis in children (CRYPTO-POC): a clinical, prospective, diagnostic accuracy study (The Lancet. Infectious diseases)

Effect of Empagliflozin on Hemodynamics in Patients With Heart Failure and Reduced Ejection Fraction (Journal of the American College of Cardiology)

Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial (BMJ (Clinical research ed.))

Risk Factors for Morbidity and Mortality Following Hospitalization for Pericarditis (Journal of the American College of Cardiology)

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis (Circulation)

EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: Definitions and management (The Journal of allergy and clinical immunology)

Ethical and Scientific Considerations Regarding the Early Approval and Deployment of a COVID-19 Vaccine (Annals of internal medicine)

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis (Nature reviews. Microbiology)

Migraine (The New England journal of medicine)