Main Researh Areas
Neurogenomics
Our primary focus is on neurogenomics research, where we leverage our expertise in genetics, genomics, epigenomics, transcriptomics, and metabolomics. This includes using multiomics approaches and machine learning methods. We are currently utilizing nanopore technology to advance our understanding of Intracranial Hypertension, Migraine, Epilepsy, and Multiple Sclerosis.
Headache Research
As part of the DHC, we conduct extensive research on different types of headaches. Our work spans Genome-wide association analysis of cluster headache, migraine, trigeminal neuralgia, neuropathies, headache resilience, treatment response, and neurological disease trajectories. We work closely with our research colleagues at Glostrup Research Park, assisting with biostatistic and bioinformatic analyses on human and animal experimental headache models, as well as more epidemiologically driven approaches for improving phenotype assessment, e.g., diagnostic criteria.
Multiple Sclerosis Research
As part of the DMSC, we connect treatment outcomes with genetic data at the molecular level, using Big Data to identify, for example, disease trajectories. Furthermore, the utilization of nanopore technology is a joint venture, exploiting the extensive existing laboratory knowledge in DMSC.
Translational Research
Our group is physically based in a translational and basic research facility called “Research Park” in Glostrup. This setup facilitates a highly functional translational research environment that ensures disease/clinically relevant research.
Academic Collaboration
Through our university affiliation, we maintain a strong connection with the academic environment, fostering a culture of continuous learning and collaboration. This includes international collaboration, and the group is part of CCG and IHGC, and nationally DBDS and CHB.
Researchers
- Associate professor, Group Leader, Thomas Folkmann Hansen
- Associate Professor, Lisette Kogelmann
- Post Doc, MD, Mona Ameri Chalmer
- Post Doc, MD, Isa Amalie Olofsson
- PhD, MSc, Tanya Techlo
Visiting Scientist
- PhD-stud Olafur Davidsson Danish Cancer Society
Associated Departments
Danish Headache Center, Danish Multiple Sclerosis Center, Translational Research Centre, Rigshospitalet
Keycollaborators
- International Headache genetics Consoritum (IHGC)
- International Consoritum on Cluster Headache Genetics (CCG)
- Coepnahgen Hospital Biobank
- Danish Blood Donor study
- Novo Nordic Foundation Center for Protein Research
- University of Oslo & Helsinki
- Laureate Institute for Brain Research
- Brigham and Women’s Hospital
- deCODE genetics
Projects
- Migraine Genomics
- Genetic risk of Trigeminal Neuralgia, Intercranial Hypertension Headache, cluster headache, post-traumatic headache, neuropati, treatment response.
- Whole genome sequencing of familial migraine and twins with migraine
- Genetic comorbidity: disease trajectories in neurological disorders
- The CylClome: Mapping migraine onto the omics atlas of the menstruation cycle