Porse Group Our research group addresses the molecular mechanisms governing both normal and malignant hematopoiesis with the aim to identify novel targets for future therapeutic intervention in patients suffering from AML. Page ContentResearch Vision Several cancers, including acute myeloid leukemias (AML), are maintained by cancer stem cells (CSCs). Similar to normal stem cells, CSCs are able to self-renew and are thus the cells that need to be targeted in order to efficiently eradicate the disease.The focus of the Porse group is therefore to study cancer from a stem-cell centric viewpoint. Specifically, we address the molecular mechanisms governing both normal and malignant hematopoiesis with the aim to identify novel targets for future therapeutic intervention in patients suffering from AML.Research FocusTo address our overall research vision, the overarching goals are to:Understand the gene regulatory mechanisms that governs the behavior of normal HSCs and myeloid lineage decision events during normal hematopoiesisUnderstand the gene regulatory mechanisms governing the behavior of leukemic stem and progenitor cellsTo use the knowledge gained from 1) and 2) to identify novel potential targets for future treatment of leukemia. By working at the interface between normal and malignant hematopoiesis we will able to gain novel insights into both processes with the ambition to translate our findings for the benefit of future leukemia patients.Orcid profile of Bo PorseOrcid profile of Bo Porse including CV and publications Last updated: 17. March 2025 Responsible editor Webgruppen på Rigshospitalet Please give your consent in order to send your message. Please enter a valid email address. Note: This mail is not secure. Your email should therefore not include civil registration numbers or health information.Read how to send secure digital post:https://www.regionh.dk/securemail Write your message: Write your email (Must be filled out): If you wish to attach one or more files you will need to login first. Create account or log in I hereby give my consent to the Capital Region of Denmark to process the information in my enquiry for professional purposes only. Read the terms for your consent No e-mail has been registred for this user/group