About
Vision:
To improve the health for all children globally.
Mission:
To ensure improved and equal health for all children by research, training and networking.
Objective:
To map and coordinate current and future international health projects, and create a platform for exchange of knowledge, experience and education in global child health.
Strategies and most important areas of work:
a. Research in low- and middle-income countries
i. Implementation research including new technologies
ii. Infectious diseases and respiratory diseases in children < 5 years of age
iii. Perinatal and neonatal diseases and survival
b. Strengthening networking and education within Denmark and with low- and middle-income
institutions including University of Copenhagen
c. Dissemination of knowledge through seminars and courses
d. Strengthening cooperation within Global Health at Copenhagen University Hospital,
Rigshospitalet
Unit coordinators:
Freddy Karup Pedersen
Professor emeritus, dr.med.
Anja Poulsen
Consultant, PhD
Jesper Kjærgaard
MD, PhD, postdoc
Stine Lund
MD, PhD
Associated researchers
 Freddy Karup Pedersen
Professor emeritus, dr.med. fped0001egionh.dk
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Anja Poulsen
Consultant, PhD anja.poulsen.01@regionh.dk
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Jesper Kjærgaard
MD, PhD, postdoc jesper.kjaergaard@regionh.dk
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Vibeke Brix Christensen
MD, PhD, DMSC
vbrixchr@gmail.com
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Charlotte Holm-Hansen
MD, PhD student charlotte.carina.holm-hansen@regionh.dk
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Malene Landbo Børresen, MD, PhD
MD, PhD mboe0097@regionh.dk
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Thomas Nørrelykke Nissen
MD, PhD Thomas.noerrelykke.nissen.02@regionh.dk
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Alexandra Kruse
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Stine Lund
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Joakim Bloch
MD, PhD student joakim.bloch@regionh.dk
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Christine Manich Bech
MD Christinemanichbech@gmail.com
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Lærke Vinge Larsen
Medical student laerke.vinge.larsen.01@regionh.dk
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Current research projects
Cooperation with Danish Vietnamese Association and Childrens Hospital nr 1, Ho Chi Minh City, Vietnam: neonatal survival. Until now included 4 PhD students.
EU project Horizon2020: FRESHAIR on childhood asthma and respiratory diseases: cooperation with institutions in Vietnam, Uganda, Kyrgyzstan, Cyprus and University of Copenhagen, department of family medicine.
Cooperation with Pemba Public Health Laboratory and Ministry of Health Zanzibar
NEO neonatal emergency outcome, PhD study, ongoing on Pemba, Tanzania 2018-2023
Neonatal use of antibiotics, master study, Pemba
Neonatal status the first 2 hours of life, master study, Pemba
CRP in children with febrile illness and neonatal children, PhD study, Pemba, In cooperation with ICARS (international Centre for Antibiotic Resistance
In preparation: Virtual reality in neonatal resuscitation, Pemba.
Developing an APP on respiratory diseases for use in Vietnam in under-fives cooperation with Seattle University
Implementation of spacers in Kyrgyzstan in cooperation with Association of Respiratory Diseases in Kyrgyzstan.
Encephalitis project in Myanmar and Nepal, in cooperation with local Paediatric Hospitals
CRP in children with respiratory diseases, PhD study, Kyrgyzstan. In cooperation with ICARS (international Centre for Antibiotic Resistance Research in refugee child health.
Safe Delivery App, educational app for emergency neonatal and obstetric care in Low- and Middle-Income Countries. In cooperation with Maternity Foundation
Other activities
Activities in preparation
- International Course in Pediatric Infectious Diseases and global Health, Bangladesh, Januar 2025
Previous activities
International Course in Pediatric Infectious Diseases and Global Health, Namibia, November 2023
International Course in Pediatric Infectious Diseases and Global Health, Kyrgyzstan, September 2022
International Course in Pediatric Infectious Diseases and Global Health, Mozambique, February 2020
Seminar on infectious disease outbreaks, a historical and contemporary perspective, October 2019
International Course in Paediatric Infectious Diseases and Global Health, Cambodia, January 2019
Seminar on environmental-/climate changes, Copenhagen, spring 2018
International Course in Paediatric Infectious Diseases, Nepal, November 2017
International Course in Paediatric Infectious Diseases and Global Health, Sri Lanka, January 2017
Seminar, The Global Burden of Non-Communicable Diseases, October 2016
International Course in Paediatric Infectious Diseases and Global Health, Ghana, January 2016
International Course in Paediatric Infectious Diseases, Cuba, January 2015
Seminar, Ebola 2014, November 2014
Publications from the unit
2023
The right antibiotic for the right neonate? A prospective observational cohort study at a district hospital in Pemba, Tanzania.
Lærke Vinge Larsen, Mathilde Languille Lassen, Stine Lund, Ulrikka Nygaard, Christine Manich Bech, Said Mzee, Said Mouhammed Ali & Anja Poulsen.
Journal of Tropical Pediatrics, 2023, 69(1), fmac116. https://doi.org/10.1093/tropej/fmac116
2022
Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.
Duncan CJA, Skouboe MK, Howarth S, Hollensen AK, Chen R, Børresen ML, Thompson BJ, Stremenova Spegarova J, Hatton CF, Stæger FF, Andersen MK, Whittaker J, Paludan SR, Jørgensen SE, Thomsen MK, Mikkelsen JG, Heilmann C, Buhas D, Øbro NF, Bay JT, Marquart HV, de la Morena MT, Klejka JA, Hirschfeld M, Borgwardt L, Forss I, Masmas T, Poulsen A, Noya F, Rouleau G, Hansen T, Zhou S, Albrechtsen A, Alizadehfar R, Allenspach EJ, Hambleton S, Mogensen
TH.J Exp Med. 2022
https://pubmed.ncbi.nlm.nih.gov/35442417/
Risk factors for neonatal sepsis in Sub-Saharan Africa: a systematic review with meta-analysis.
Christine Manich Bech, Christina Nadia Stensgaard, Stine Lund, Charlotte Holm Hansen, Jesper Sune Brok, Ulrikka Nygaard & Anja Poulsen.
BMJ Open 2022
https://bmjopen.bmj.com/content/12/9/e054491
Essential newborn care practices for healthy newborns at a district hospital in Pemba, Tanzania: a cross-sectional observational study utilizing video recordings.
Christina Nadia Stensgaard, Christine Manich Bech, Charlotte Holm- Hansen, Tine Bruhn Skytte, Said Mohammed Ali, Ulfat Amour Mohd, Jesper Kjærgaard, Gorm Greisen, Anja Poulsen & Stine Lund.
Global Health Action
https://pubmed.ncbi.nlm.nih.gov/35674453/
Video recording as an objective assessment tool of health worker performance in neonatal resuscitation at a district hospital in Pemba, Tanzania: a feasibility study.
Charlotte Carina Holm-Hansen, Anja Poulsen, Tine Bruhn Skytte, Christina Stensgaard, Christine Manich Bech, Mads Nathaniel Lopes, Mads Kristiansen, Jesper Kjærgaard, Said Mzee, Said Mouhammed Ali, Shaali Ame, Jette Led Sorensen, Gorm Greisen & Stine Lund.
BMJ Open 2022
https://bmjopen.bmj.com/content/12/5/e060642
Herpes simplex-virusinfektion hos nyfødte.
Stine Lund, Tine Brink Henriksen, Anja Poulsen, Kia Hee Schultz Dungu, Emma Louise Malchau Carlsen, Bo Mølholm Hansen, Lise Aunsholt & Ulrikka Nygaard
Ugeskr Læger 2022;184:V11210869
https://ugeskriftet.dk/videnskab/herpes-simplex-virusinfektion-hos-nyfodte
Essential Newborn Care practices of healthy newborns at a district hospital in Pemba, Tanzania: a cross sectional observational study using video recordings.
Christina Steensgaard, Christine Manich Bech, Charlotte Holm-hansen, Tine Bruhn Skytte, Said Mohammed Ali, Ulfat Amour Mhod,Jesper Kjærgaard, Gorm Greisen, Anja Poulsen & Stine Lund.
Global Health Action 2022
https://www.tandfonline.com/doi/full/10.1080/16549716.2022.2067398
2021
Management of Children with Respiratory Symptoms in Primary Care Facilities in Uganda: A FRESH AIR Descriptive Study
Nantanda R, Bloch J, Østergaard MS, Kirenga BJ, Tumwine JK, Ndeezi G, Reventlow S, Poulsen A & Kjærgaard J.
Health Workers' Practices in Assessment and. J Trop Pediatr. 2021 May https://academic.oup.com/tropej/article/67/2/fmab042/6296314?login=false
Bite wounds from dogs, cats and humans
Christine Manich Bech, Stine Lund, Jonas Ingemann Baggesgaard, Christina Nadia Christoffersen, Jesper Kjærgaard & Anja Poulsen
Ugeskr Laeger 2021
https://ugeskriftet.dk/videnskab/bidsar-fra-hunde-katte-og-mennesker
Indirect effects of the COVID-19 pandemic on mortality of mothers and children in low- and middle-income countries
Christine Manich Bech, Joakim Bloch, Jesper Kjærgaard, Stine Lund, Freddy Karup Pedersen & Anja Poulsen.
Ugeskr Laeger 2021
https://pubmed.ncbi.nlm.nih.gov/33734073/
Analysis of Hepatitis B Virus Genotype D in Greenland Suggests the Presence of a Novel Quasi-Subgenotype.
de Bernardi Schneider A, Osiowy C, Hostager R, Krarup H, Børresen M, Tanaka Y, Morriseau T, Wertheim JO.
Front Microbiol 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843931/
Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study.
Do CHT, Børresen ML, Pedersen FK, Nguyen TT, Nguyen HT, Kruse AY.
J Trop Pediatr. 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948389/
Health screening among children newly granted asylum in Denmark.
Nicoline Willum Frederiksen,, Nanna Marie Christoffersen, Anna Karen Haugaard, Afsaneh Ahmadi, Anja Poulsen, Marie Norredam & Alexandra Kruse.
Acta Paediatrica 2021
https://onlinelibrary.wiley.com/doi/10.1111/apa.15879
A systematic approach to context-mapping to prepare for health interventions: development and validation of the SETTING-tool in four countries.
Brakema EA, vand der Keij RM, Poot CC, Chavannes NH, Tsiligianni I, Walusimbi S, An PL, Sooronbaev T Numans ME Crone MR, Reis RR & FRESH AIR collaborators.
BMJ Glob Health 2021
https://gh.bmj.com/content/6/1/e003221
2020
No time for change? Impact of contextual factors on the effect of training primary care healthcare workers in Kyrgyzstan and Vietnam on how to manage asthma in children - A FRESH AIR implementation study.
Jesper Kjærgaard, Thomas Nørrelykke Nissen, Elvira Isaeva; Nguyen Nhat Quynh; Susanne Reventlow, Stine Lund, Talant Sooronbaev, Pham Le An, Marianne Stubbe Østergaard, James Stout & Anja Poulsen
BMC Health Services Research 2020
https://pubmed.ncbi.nlm.nih.gov/33302935/
Snakebites
Eggert S, Kjærgaard J & Poulsen A.
Ugeskr Laeger 2020
https://pubmed.ncbi.nlm.nih.gov/32800051/
Let's stop dumping cookstoves in local communities. It's time to get implementation right.
Brakema EA, van der Kleij RM, Vermond D, van Gemert FA, Kirenga B, Chavannes NH, et al.
NPJ Prim care Respir Med 2020
https://pubmed.ncbi.nlm.nih.gov/31924825/
Implementing a context-driven awareness programme addressing household air pollution and tobacco: a FRESH AIR study.
Brakema EA, van Gemert FA, Williams S, Sooronbaev T, Emilov B, Mademilov M, et al.
NPJ Prim care Respir Med 2020
https://pubmed.ncbi.nlm.nih.gov/33024125/
Rates of rehospitalisation in the first 2 years among preterm infants discharged from the NICU of a tertiary children hospital in Vietnam: a follow-up study.
Do CHT, Børresen ML, Pedersen FK, Geskus RB & Kruse AY.
BMJ Open. 2020
https://pubmed.ncbi.nlm.nih.gov/33020086/
2019
Asthma in children under 5 years in rural Kyrgyzstan: A diagnostic vacuum? A qualitative FRESH AIR study.
Østergaard MS, Kjærgaard J, Kristensen M-M, Reventlow S, Poulsen A, Isaeva E, et al.
Eur Med J Respir 2019
https://www.emjreviews.com/respiratory/article/asthma-in-children-under-5-years-in-rural-kyrgyzstan-a-diagnostic-vacuum-a-qualitative-fresh-air-study/
Effects and acceptability of implementing improved cookstoves and heaters to reduce household air pollution: a FRESH AIR study.
van Gemert F, de Jong C, Kirenga B, Musinguzi P, Buteme S, Sooronbaev T, et al.
NPJ Prim care Respir Med 2019
https://pubmed.ncbi.nlm.nih.gov/31417087/
Infectious diseases detected by screening after arrival to Denmark in internationally adopted children.
Nielsen AV, Kjaergaard J, Pedersen TM, Helmuth IG, Nygaard U, Nielsen HW, et al.
Acta Paediatr 2019
https://pubmed.ncbi.nlm.nih.gov/31580515/
Diagnosis and treatment of acute respiratory illness in children under five in primary care in low-, middle-, and high-income countries: A descriptive FRESH AIR study.
Kjærgaard J, Anastasaki M, Østergaard MS, Isaeva E, Akylbekov A, Nguyen NQ, et al.
PLoS One 2019
https://pubmed.ncbi.nlm.nih.gov/31693667/
COPD's early origins in low-and-middle income countries: what are the implications of a false start?
Brakema EA, van Gemert FA, van der Kleij RMJJ, Salvi S, Puhan M, Chavannes NH, et al.
NPJ Prim care Respir Med 2019
https://pubmed.ncbi.nlm.nih.gov/30837469/
The socioeconomic burden of chronic lung disease in low-resource settings across the globe - an observational FRESH AIR study.
Brakema EA, Tabyshova A, van der Kleij RMJJ, Sooronbaev T, Lionis C, Anastasaki M, et al.
Respir Res 2019
https://pubmed.ncbi.nlm.nih.gov/31864411/
Neurodevelopment at two years corrected age among Vietnamese preterm infants.
Chuong HTD, Kruse YA, Wills B, Saraswathy S, Clapham H, Pedersen FK, Pham NT, Vu MP & Borresen ML
Arch Dis Child 2019
https://adc.bmj.com/content/105/2/134
Physical growth of Vietnamese preterm infants-a follow up study.
Chunong HTD, Borresen ML, Pederen FK, Geskus R B, Kruse AY.
Part of Chuong HTDs phd thesis at the University of Copenhagen November 2019.
Rehospitalisation of Vietnames preterm infants in the first two years of life – a follow up study.
Chuong HTD, Borresen ML, Pedersen FK, Gestus RB, Kruse AY.
Part of Chuong HTDs phd thesis at the University of Copenhagen November 2019.
Changing patterns of neurodevelopmental outcomes from 12 months to 24 months corrected age among Vietnames preterm infants.
Chuong HTD, Borresen ML, Pedersen FK, Kruse YA.
Part of Chuong HTds phd thesis at the Unvoiersity of Copenhagen November 2019.
To bubble or not? Review of bubble continuous positive airway pressure in children in low- and middle-income countries
Stagstrup C, Nørgaard M, Lund S & Poulsen A
J Trop Pediatr. 2019
https://pubmed.ncbi.nlm.nih.gov/31599959/
The effect of smartphone training of Ghanaian midwives by the Safe Delivery application on the incidence of postpartum hemorrhage: A cluster randomized controlled trial.
Klokkenga C M B, Enemark U, Adanu R, Lund S, Sørensen B L, Attermann J.
Cogent Medicine 2019.
https://www.tandfonline.com/doi/full/10.1080/2331205X.2019.1632016
Health workers' experiences with the Safe Delivery App in West Wollega Zone, Ethiopia: a qualitative study.
Thomsen CF, Barrie AMF, Boas IM, Lund S, Sørensen BL, Oljira FG, et al.
Reproductive Health. 2019.
https://pubmed.ncbi.nlm.nih.gov/31072399/
2018
Recurrent lower respiratory illnesses among young children in rural Kyrgyzstan: overuse of antibiotics and possible under-diagnosis of asthma. A qualitative FRESH AIR study.
Østergaard MS, Kjærgaard J, Kristensen M-M, Reventlow S, Poulsen A, Isaeva E, et al.
NPJ Prim care Respir Med. 2018
https://www.nature.com/articles/s41533-018-0081-y
Mobile phone innovations for maternal and neonatal health in low- and middle-income countries: the role of mHealth.
Lund S.
BJOG. 2018
https://pubmed.ncbi.nlm.nih.gov/29927534/
2017
Audit of neonatal deaths in a provincial Hopspital in Vietnam.
Binh TT, Hue TH, Kruse AY, Phuong N, Cam, Pedersen FK.
Part of Binh TTs Phd thesis at the University of Copenhagen September 2017.
Incidence of hypoxic-ischemic encephalopathy in a Vietnamese population with a high rate of caesarean delivery.
Binh TT, Thuy TM, Chung, Ha TD, Nguyen, Loi QT, Phuc HH, Anh TTN, Pedersen FK.
Pat of Binh TTs Phd thesis at the University of Copenhagen September 2017.
Whole body cooling: a safe and feasible procedure for neonates with hypoxic ischemic encephalopathy in Vietnam.
Binh TT, Phuon NC, Dung TNL, Thuy TAN, Pedersen FK
Part of Binh TTs thesis at the University of Copenhagen September 2017.
Infant botulism in Denmark from 1995 to 2015.
Drivenes B, Krause TG, Andersson M, Müller L, Fuursted K, Pedersen T, Hansen AK, Børresen ML.
Dan Med J. 2017 Sep
https://www.ncbi.nlm.nih.gov/pubmed/28874241
CPT1A Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders.
Skotte L, Koch A, Yakimov V, Zhou S, Søborg B, Andersson M, Michelsen SW, Navne JE, Mistry JM, Dion PA, Pedersen ML, Børresen ML, Rouleau GA, Geller F, Melbye M, Feenstra B.
Circ Cardiovasc Genet. 2017 Jun
https://www.ncbi.nlm.nih.gov/pubmed/28611031
Effect of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage by respiratory pathogens among Greenlandic children.
Navne JE, Koch A, Slotved HC, Andersson M, Melbye M, Ladefoged K, Børresen ML.
Int J Circumpolar Health. 2017
https://www.ncbi.nlm.nih.gov/pubmed/28467237
2016
South Vietnamese rural mothers knowledge, aTTITUDE and pRACTICE (KAP) in child health care.
Dinh Thac2, Freddy Karup Pedersen1, Tang Chi Thuong2, Le Bich Lien2, Nguyen Thi Ngoc Anh3, Nguyen Ngoc Phuc3.
Biomed Research International March 2016.
Low neonatal mortality and high incidence of infectious diseases in a Vietnamese Provincial Hospital.
Binh TT, Kruse AY, Hue TH, Phuong N, Pedersen FK.
Biomed research International, ID2087042, Volume 2016
Nasopharyngeal bacterial carriage in young children in Greenland: a population at high risk of respiratory infections.
Navne JE, Børresen ML, Slotved HC, Andersson M, Melbye M, Ladefoged K, Koch A.
Epidemiol Infect. 2016 Nov
https://www.ncbi.nlm.nih.gov/pubmed/27405603
Effects of the Safe Delivery App on quality of care and perinatal survival in Ethiopia: A cluster-randomized controlled
Lund S, Boas I M, Bedesa T, Fedeke W, Nielsen H S, Sørensen B L. trial.
JAMA Pediatr, 2016
2015
The diagnosis and treatment of Helicobacter pylori infection in Arctic regions with a high prevalence of infection: Expert Commentary.
McMAHON BJ, Bruce MG, Koch A, Goodman KJ, Tsukanov V, Mulvad G, Borresen ML, Sacco F, Barrett D, Westby S, Parkinson AJ.
Epidemiol Infect. 2015 Jun
http://www.ncbi.nlm.nih.gov/pubmed/26094936
Determination of NAT2 acetylation status in the Greenlandic population.
Geller F, Soborg B, Koch A, Michelsen SW, Bjorn-Mortensen K, Carstensen L, Birch E, Nordholm AC, Johansen MM, Børresen ML, Feenstra B, Melbye M.
Arch Toxicol. 2015 Mar
http://www.ncbi.nlm.nih.gov/pubmed/25794903
Hepatitis B prevalence and incidence in Greenland: a population-based cohort study.
Børresen ML, Andersson M, Wohlfahrt J, Melbye M, Biggar RJ, Ladefoged K, Panum I, Koch A.
Am J Epidemiol. 2015 Mar
2014
http://www.ncbi.nlm.nih.gov/pubmed/25721415
Climate change and infectious diseases in the Arctic: establishment of a circumpolar working group.
Parkinson AJ, Evengard B, Semenza JC, Ogden N, Børresen ML, Berner J, Brubaker M, Sjöstedt A, Evander M, Hondula DM, Menne B, Pshenichnaya N, Gounder P, Larose T, Revich B, Hueffer K, Albihn A.
Int J Circumpolar Health. 2014 Sep
http://www.ncbi.nlm.nih.gov/pubmed/25317383
Mobile Phone Intervention Reduces Perinatal Mortality in Zanzibar: Secondary Outcomes of a Cluster Randomised Controlled Trial.
Lund S, Rasch V, Hemed M, Boas I M, Said A, Said K, Makundu M H, Nielsen B B.
JMIR Mhealth and Uhealth 2014
Mobile phones improve antenatal care attendance and quality of care in Zanzibar: A cluster randomised controlled trial.
Lund S, Nielsen B B, Hemed M, Boas I M, Said A, Said K, Makungu M H, Rasch V.
BMC Pregnancy and Childbirth 2014,14:29.
2013
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Identification of important and potentially avoidable risk factors in a prospective audit study of neonatal deaths in a paediatric hospital in Vietnam.
Alexandra Y Kruse, Cam N Phuong2, Binh TT Ho2, Lone G Stensballe3, Freddy K Pedersen, Gorm Greisen
Acta Paed, 2013 Sep
Neonatal Blood Stream Infections in a Pediatric Hospital in Vietnam: a Cohort Study.
Kruse AY, Chuong DHT, Phuong CN, Duc T, Stensballe LG, Prag J, Kurtzhals J, Greisen G, Pedersen FK.
J Trop Pediatr 2013 July