Main medical speciality: Internal medicine: haematology
Main research areas
Red Blood Cells and Iron
Our traditional core focus is translational research in classic hematology, especially iron metabolism and herediatry anemias such as hemoglobinopathies, membranopathies, and enzymopathies.
Clinical trials
As the Nordic reference center for hereditary anemias, we run numerous both commercial and investigator-initiated trials that may benefit our patients.
Epidemiology
Utilizing large Danish general population cohorts and the UK biobank, we study all aspects of hematology, which may lay the foundation for a rational work-up and treatment of individuals with all types of common clinical issues in hematology.
Researchers
- Jens Helby Petersen, MD, PhD, senior researcher
- Jesper Petersen, PhD, Head of lab, senior researcher
- Amina Nardo-Marino, MD, PhD, postdoc
- Mathis Motelsen, MD, PhD student
- Anne Rudbeck Juhl, MD, PhD student
- Esther Agnethe Ejskjær Gravholt, pregraduate student
- Rebekka la Cour Hillingsø, research year student
- Selma Kofoed Bendtsen, MSc
Key collaborators
- ERN-EuroBloodNet
- Richard van Wijk, Associate professor
Benign Hematology Center, Van Creveldkliniek, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands
- David Rees, Professor
Department of Paediatric Haematology, King's College Hospital NHS Foundation Trust, King's College London, London, UK
- Thomas Williams, Professor
KEMRI-Wellcome Trust Research Programme Kilifi, Kenya
- Nicolai Jacob Wewer Albrechtsen
Novo Nordisk Foundation Center for Protein Research
University of Copenhagen
Projects
Danish Hereditary Anemia Database
- Contact Person: Senior Physician Andreas Glenthøj
- Disease Group: Patients suspected or diagnosed with a hereditary anemia
- Purpose: Combine advanced diagnostic tests to ensure patients with anemia a correct diagnosis, facilitate collaboration across regional boundaries in Denmark, and provide the best possible treatment for patients with anemia.
Autoimmunity in Bone Marrow Failure
- Contact person: Senior Physician Andreas Glenthøj and Senior Physician Ulrik Overgaard
- Disease Group: Primarily patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and/or Aplastic Anemia (AA).
- Purpose: The purpose of the trial is to investigate autoimmunity against stem cells in the bone marrow in conditions with bone marrow failure. The goal is to provide a basis for targeted treatment of these conditions.
Autoimmunity in Immune Thrombotic Thrombocytopenic Purpura
- Contact person: Senior Physician Andreas Glenthøj and Senior Physician Ulrik Overgaard
- Disease Group: Primarily patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and/or Aplastic Anemia (AA).
- Purpose: The purpose of the trial is to investigate underlying autoimmunity and provide basis for targeted treatment of these conditions.
Hereditary Hemolysis in a General Population Study
- Student: Mathis Mottelson, PhD student
- Purpose: Investigate the prevalence of and risks associated with hemolysis through the major Danish population surveys.
Hemochromatosis
- Student: Mathis Mottelson, Ph.D. student
- Purpose: Study as-yet unknown complications of hemochromatosis by exploiting the major Danish population cohorts.
Thrombocytopenia and Risk of Cancer and Death
- Student: Anne Rudbeck Juhl, Ph.D. student
- Purpose: Study risks associated with a low number of platelets (thrombocytes) through the extensive Danish population cohorts and the UK biobank in order to generate an evidence-based approach to managing individuals with a low number of platelets.
Examining the association between malaria and splenic injury in children with sickle cell anaemia
- Contact person: Amina Nielsen Nardo-Marino, MD, Ph.D, Postdoc
Funding
Since 2016, the Danish Red Blood Cell Center has received research funding from:
- Agios
- Alexion
- Beckett-Fonden
- BMS
- Boserup-fonden
- British Society of Haematology
- Dagmar Marshal's Foundation
- ERN-EuroBloodNet
- Independent Research Fund Denmark
- Herlev and Gentofte Research Foundation
- Department of Clinical Medicine Research Foundation, University of Copenhagen
- Independent Research Fund Denmark
- Innovation Fund Denmark
- Karla og Verner Sørensens Nonprofit Research Fund
- Danish Cancer Society
- Novo Nordisk A/S
- Novo Nordisk Foundation
- Reinholdt W. Jorck and Wife Fund
- Rigshospitalet Research Foundation
- Saniona A/S
- Sanofi A/S