Lab members
Sarah Louise Tangsgaard Christensen, Rikke Holm Rasmussen, Karina Obelitz-Ryom, Caroline Degel, Leonora Wang Sperling, Song Guo, Lubna Al-Ansari
Background
Decades of human experimental migraine studies have revealed several mechanisms to induce migraine attacks that must be further dissected in preclinical experiments.
The MiND lab investigates neurovascular mechanisms underlying migraine pain and other headache disorders. We study how meningeal blood vessels and immune cells communicate with trigeminal sensory nerves to promote pain signaling. Combining molecular approaches, advanced imaging, and translational animal models, we seek to uncover the biological processes that drive headache and identify new therapeutic targets.
Physically, the MiND lab is placed at the Translational Research Centre (Trace) located at Copenhagen University Hospital – Rigshospitalet, Glostrup which offers excellent facilities for experimental research and clinical collaborations. Furthermore, our lab sections to the Center for Translational Neuromedicine at University of Copenhagen, a strong neuroscience partner.
Current projects
Our current research funded by the Novo Nordisk foundation and Independent Research Fund Denmark focuses on nitric oxide homeostasis and its contribution to migraine relevant pain generation within the meninges and trigeminovascular system. We are involved in national and international academic collaborations on animal behavioral assays and meningeal mechanosensation, and have ongoing collaborations with biotech partners.
Links
Updated: 08-09-2026