Cluster headache

​Read more about the research group's members, background, current projects and collaboration.​


Rigmor Højland Jensen, Mads Barløse, Nunu Lund, Anja Petersen, Agneta Snoer, Marie-Louise Søborg.


Cluster headache is one of the most severe and disabling type of headaches. The pathophysiology of this disorder is largely unknown and it may be very difficult to treat, in particular the chronic form of cluster headache. There is a peculiar but yet unclarified relation between cluster headache and sleep as most of these severe headache attacks occur during the night, believed to be caused by a hypothalamic disturbance in the chronobiology.

Current projects

Analysis of socio-economic burden of cluster headache have been finalized and prepared for publication.

Current projects include examination of shift of phenotype, prediction of bout and founding of a biobank, comparing biomarkers of chronic and episodic cluster headache patients and healthy headache-free-controls.

In addition, the Cluster headache group is participating in two treatment multicenter trials. Treatment of both episodic and chronic cluster headache with anti-CGRP (eptinizumab) for Lundbeck and treatment of chronic cluster-headache with TENS and ONS-stimulation in collaboration with University Hospital of Aarhus.


Ass. Prof Thomas Folkman Hansen, Neurogenetics,  Rigshospitalet-Glostrup, Jørgen Rostgaard, CMT surgeon, DDS, Department of Oromaxillofacial Surgery, National Hospital, Copenhagen, Denmark, Prof. Poul Jennum, Danish Center for Sleep Medicine, Rigshospitalet-Glostrup, Prof. Niklas Rye Jørgensen, Department of biochemistry, Rigshospitalet-Glostrup, Prof. Anders Juul, Department of fertility, Rigshospitalet-Blegdamsvej, Lundbeck Pharma, Ottiliavej 9, Valby, Copenhagen, Denmark, Ass. Prof. Kaare Meier, and Professor Jens-Christian Hedemann Sørensen, Department of Anaesthesiology and Neuro-surgery, University Hospital of Aarhus

Updated: 12-01-2022

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