The introduction of novel technologies into the monitoring of perinatal health

A prospective cohort study of the predictive value of the Salurate test-device for preeclampsia and related outcomes. A qualitative interview study of pregnant womens attitude towards self-monitoring using a telemedic solution.In addition a clinical study of uric acid in saliva, maternal blood, amniotic fluid and cord blood during childbirth.

​​A research project by Ida Catharina Püschl

Background
Preeclampsia is a major cause of maternal and fetal morbidity and mortality, which may manifest rapidly at any time after week 20 of gestation. Despite research efforts, there is currently no effective screening test to identify which pregnant women will develop preeclampsia. In a pilot study of 137 maternities reported by the University of Southampton (2015, Bas van Rijn et al.), monitoring the weekly salivary uric acid levels in pregnant women indicated potential to enhance predictive capability for pre-eclampsia and related outcomes. Based on this, Morgan Innovation and Technology has invented a hometest suitable for self-monitoring of salivary uric acid levels –the ”Salurate”-test-device. The test is operated by a telemedical solution using a smartphone app.

Aim
In a prospective cohort study of 563 pregnant women: investigate the predictive potential of salivary uric acid in relation to the development of pre-eclampsia and secondary outcomes.

20 women participating in qualitative interviews
Exploring pregnant womens attitude towards self-monitoring using a telemedic solution.

30 women during labor
Investigating the origin of raised salivary uric comparing levels in saliva, blood, amniotic fluid and cord blood in maternal vs fetal distress.



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