Our research/the group
Research in the Porse group is focused on elucidating mechanisms governing normal and malignant hematopoiesis with special emphasis on the behaviour of hematopoietic stem cells (HSCs) during adult hematopoiesis and leukemic stem cells (LSCs) in acute myeloid leukemia. To this end, we employ mouse models of human AML, mouse knock-out lines of putative HSC/LSC regulators, primary patient material and a broad range of bioinformatics tools. We have also conducted a number of shRNA-based in vivo screens for genes involved in tumor maintenance and identified a number of novel potential oncogenes and tumor suppressors which will be studied in future projects.
Porse group is affiliated with the Finsen Laboratory www.finsenlab.dk at Rigshospitalet as well as BRIC www.bric.ku.dk and DanStem www.danstem.ku.dk, both University of Copen-hagen.
Project/the research project(s)
A number of projects under the headlines listed below are available for the successful applicants.
- Characterisation of novel candidate oncogenes and tumor suppressors in AML
- Characterisation of putative HSC/LSC regulators
- In vitro approaches for the generation and/or maintenance of HSCs
- Bioinformatics analyses of genome-wide datasets (Chip-seq and/or gene expression experiments) in normal and malignant hematopoiesis
Candidates with both wet-lab and bioinformatics backgrounds are encouraged to apply.
Start: Preferably late 2015 or after agreement
Duration: 2 years respectively 3 years
We expect you to be a highly motivated and highly ambitious scientist with the following qualifications:
- A PhD in Life Sciences
- Strong documented research experience in either mouse genetics, advanced flow cytometry, chromatin immuno precipitation, functional hematopoiesis or bioinformatics.
- Candidates with combined experiences are particularly encouraged to apply.
- Strong molecular biology background and/or experience with bioinformatics processing of NGS/micro-array data sets is an advantage
- Excellent English skills, written and spoken
Place of employment
The employment is at BRIC, University of Copenhagen, while place of work will be Finsen Laboratory; both located in the Biocenter, close to the centre of Copenhagen. We offer cre-ative and stimulating working conditions in a dynamic and international research environ-ment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/
Terms of salary and employment
Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at 32.095 DKK/approx. 4.250 Euros plus pension. Depending on qua-lifications, a higher salary may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions if holding a PhD degree and if they have not lived in Denmark during the past ten years.
For further information regarding the position, please contact Professor Bo Porse on firstname.lastname@example.org
Your application for must be submitted electronically by clicking ‘Apply now’ below or via BRICs website on http://www.bric.ku.dk/jobs/ The application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page)
- CV incl. education, work/research experience, language skills and other skills relevant for the position
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications
Letters of recommendation
Furthermore, the applicant should provide two letters of recommendation. To be taken into consideration, the letters must be signed by the supporting persons on paper with institu-tional letter head and in PDF format. The letters should be received before deadline on email@example.com with subject “name candidate-Porse-postdoc-Sept2015”; preferably by the supporting persons. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.
Application deadline: 23 September 2015.
We reserve the right not to consider applications or supplementary material received after deadline, and not to consider applications or letters of recommendation that do not live up to the above-mentioned requirements.
The further process
Shortlist: After expiry of the application deadline, the superior with power to appoint selects a number of applicants for assessment on the advice of the Appointments Committee. All applicants are immedi-ately notified whether their application has been passed for assessment. Applicants who were not passed for assessment should not expect further with regard to their application unless the shortlist is revised.
Assessment: The selected applications will be assessed according to the Ministry Order on the Appoint-ment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement.
You can read about the recruitment process at http://employment.ku.dk/faculty/
BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.