Staff in Department of Pathology

Eva Løbner Lund, MD, PhD, Consultant neuropathologist

Diagnostic areas of interest: Neuropathology, ophtalmic pathology and pathology of peripheral nerves, including postmortem neuropathological examinations of neurodegenerative diseases.

The neuropathology service includes examination of specimens from the neurosurgical department, mostly CNS tumors, but also resections from epilepsy surgery and other diseases in which diagnostic brain biopsies are needed. 

Peripheral nerve examination includes peripheral nerve biopsies and evaluation of small fiber neuropathy in skin biopsies from the neurological department.

Ophthalmic pathology consists of specimens from all ophthalmologists in Denmark, including uveal and conjunctival melanomas, retinoblastomas and specimens from all other eye diseases in which diagnostic histopathology is required. 

Post mortem neuropathological examinations include suspected Creutzfeldt-Jakob´s disease cases from all of Denmark and forensic cases.

Research areas of interest:  Inflammatory microenvironment in neurodegenerative diseases and tumors, with special focus on Creutzfeldt-Jakob’s disease. 

Current positions:
  • Consultant neuropathologist, Department of Pathology, Rigshospitalet, Copenhagen, Denmark
  • Clinical associate professor, University of Copenhagen
  • President, Danish Pathology Society
Previous work experience:
  • 2012 – 2014: Staff Specialist at Laboratory of Neuropathology, Department of Pathology, Rigshospitalet, Copenhagen
  • 2011: Staff specialist in general pathology, Bispebjerg hospital, Copenhagen.
  • 2006 – 2011: Specialist education in general pathology. Pathology departments at Bispebjerg Hospital, Rigshospitalet and Hillerød Hospital.
  • 1996 – 2006: Research assistant, Ph.d.-student, assistant professor and associate professor at Dept. of Molecular Pathology, University of Copenhagen. Research focus on tumor angiogenesis and tumor microenvironment in glioblastoma and lung cancer models
  • 1990 – 1998: Hospital physician at departments of surgery, rheumatology, medicine and oncology.
Education and training:
  • 2011: Danish board certification in pathology 
  • 2001: University of Copenhagen, PhD dissertation. Title of thesis: “Blood vessels in human tumor xenografts. Angiogenesis, adaptation to therapy and the role of the microenvironment.”
  • 1990: Århus University: Cand. Med. (MD)
Karsten Buschard, Professor, MD, DMSc, DVSc

I am team leader of the diabetes department at Bartholin institute, Department of pathology, Rigshospitalet. I am educated as an MD and after 6 years of clinical training, I have ever since worked in medical research where my main interest is to understand and prevent development of type 1 diabetes. As seen from my Curriculum Vitae I have suggested several new principles in this respect, which include rest of beta cells, intake of gluten-free diet and influence on the glycosphingolipid metabolism. Currently I am head of a research group of up to 10 dedicated persons. 

Among specific research projects the gluten-free diet studies can be mentioned. In 1999 we published, as the first worldwide, that intake of gluten-free diet dramatically reduces the diabetes incidence in NOD mice. This has been confirmed in several other studies, and also in human type 1 diabetic patients a better remission period can be obtained by giving this diet. Even some patients can come out of insulin treatment for 1-2 years. Among the mechanisms for these beneficial effects can be mentioned changes in the intestinal flora (more Akkermancia), less permeability of the intestinal barrier, less activity of some immune cells (natural killer cells, dendritic cells) and less activity of the beta cells.

CV - Karsten Buschard

Laurits Juulskov Holm, MSc Biochemistry, PhD Student

Areas of interest: Molecular cell biology, lipid biology, diabetes, sphingolipids, GWAS, animal experimentation 

Project description: Affiliated to the Bartholin Institute, Rigshosiptalet and the Copenhagen center for Glycomics, University of Copenhagen

I work with a type of sphingolipid called sulfatide which is present in the insulin producing islets of Langerhans where it is known to be involved in many aspects of cell biology. 

The project is concentrated around understanding the role of sulfatide and other sphingolipid during the development of type 1 diabetes. This is done using human samples combined with mice experiments and cell cultures.

In the long term the aim is to prevent development of type 1 diabetes through modulation of sphingolipid metabolism.

> CV - Laurits Juulskov Holm
Tina Zenia Jørgensen- PhD Student, Cand.scient. in Molecular Biomedicine

Affiliated to The Bartholin Instiute, Rigshospitalet, Denmark. 

Development of type 1 diabetes depends on many environmental factors including gluten. I am studying the immunological mechanisms underlying the preventive effects of gluten-free diet administered to the diabetes-prone NOD mouse strain. 

Expertise: Mouse studies, Flow cytometry, in vitro cultivation and proliferation

> CV - Tina Zenia Jørgensen

Vera Timmermans-Wielenga, DMSc, Pathologist, Head of dept. of Pathology

Areas of interest: Medical doctor, Pathologist, MD PhD. Head of Pathology Dept, Rigshospitalet. 

Expertise and objectives: Strategic leadership within Public Health with focus on professionalism, content & continuing education, innovation & efficiency, building alliances & shearing of knowledge.  

The Pathology Department at Rigshospitalet, delivers diagnostic expertise according to international standards to Denmarks most specialised hospital and is characterised by a thriving academic research environment, integrated in efficient patient care within all pathology subspecialties.  

Personal continuing education & development: Ongoing courses on leadership & management at a.o. INSEAD and Harvard Medical School 

Current activities: We are currently organizing a pathology course together with MD Anderson Pathology: 

We expect the department to deliver all diagnostics digitally soon. The laboratory is already digitized with computer support of every step of the specimen analysis. throughput. In addition, we engage three consultant pathologists performing digital diagnostics, of which two pathologist from abroad. 

The department's is to be fully digitized on all areas within the coming two years.

> CV - Vera Timmermans-Wielenga

> Publications under Wielenga 

Publications under Timmermans-Wielenga

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