The Multiple Sclerosis Clinic and Clinic for Optic Neuritis, Rigshospitalet
Professor Jette Frederiksen
The blood-brain barrier and brain metabolism in optic neuritis, neuromyelitis optica spectrum disorders and the early phases of multiple sclerosis are studied using multimodal MRI.
Southampton Clinical and Experimental Neurology Team, University of Southampton
Associate Professor Ian Galea
Neuroinflammation, blood and urine biomarkers of inflammation and the effects of systemic infection on the blood-brain barrier in multiple sclerosis are investigated using dynamic contrast enhanced MRI (DCE-MRI).
Varatharaj A, Liljeroth M, Darekar A, Larsson HBW, Galea I, Cramer SP. Blood-brain barrier permeability measured using dynamic contrast-enhanced magnetic resonance imaging: a validation study. J Physiol. February 2019. 597(3):699-709.
Center for Neuropsychiatric Schizophrenia Research
Professor Birthe Glenthøj
The neurobiology of schizophrenia and the development of psychiatric disease are investigated. Brain function and anatomy is examined using brain connectivity MRI, task-based functional MRI and structural imaging.
Legind CS, Broberg BV, Brouwer R, Mandl RCW, Ebdrup BH, Anhøj SJ, Jensen MH, Hilker R, Fagerlund B, Hulshoff Pol HE, Glenthøj BY, Rostrup E. Heritability of Cerebral Blood Flow and the Correlation to Schizophrenia Spectrum Disorders: A Pseudo-continuous Arterial Spin Labeling Twin Study. Schizophr Bull. February 2019. doi: 10.1093/schbul/sbz007.
Wulff S, Nielsen MØ, Rostrup E, Svarer C, Jensen LT, Pinborg L, Glenthøj BY. The relation between dopamine D2 receptor blockade and the brain reward system: a longitudinal study of first-episode schizophrenia patients. Psychol Med. January 2019.15;:1-9.
The Danish Headache Center, Rigshospitalet
Professor Messoud Ashina
The pathophysiology and treatment of migraine is studied in spontaneous migraine attacks and in human headache models. High-resolution MRI angiogram and functional imaging methods is used to examine vessel dilation, cerebral perfusion, metabolism and blood-brain barrier permeability.
Arngrim N, Hougaard A, Ahmadi K, Vestergaard MB, Schytz HW, Amin FM, Larsson HBW, Olesen J, Hoffmann MB, Ashina M. Heterogenous migraine aura symptoms correlate with visual cortex functional magnetic resonance imaging responses. Ann Neurol. December 2017. 82(6):925-939.
Hougaard A, Amin FM, Christensen CE, Younis S, Wolfram F, Cramer SP, Larsson HBW, Ashina M. Increased brainstem perfusion, but no blood-brain barrier disruption, during attacks of migraine with aura. Brain. June 2017.1;140(6):1633-1642.
Amin FM, Asghar MS, Hougaard A, Hansen AE, Larsen VA, de Koning PJ, Larsson HB, Olesen J, Ashina M. Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study. Lancet Neurol. May 2013. 12(5):454-61.
Center for Neuropsychiatric Depression Research
Professor Poul Videbech
The effect of depression treatment is examined using brain connectivity MRI and structural imaging.
Neurobiology research Unit, Rigshospitalet
Professor Olaf Paulson
Investigation of using high field strength 7T MRI in the clinical evaluation of neurological disease.
Center for Healthy Ageing, University of Copenhagen
Professor Martin Lauritzen
The declining brain health and changes in brain structures as part of the ageing process is examined in multimodal population-based cohort studies.
Steno Copenhagen Diabetes Center
Professor Peter Rossingwww.sdcc.dk
How the brain physiology and metabolism is affected from diabetic disease is investigated.