Post doctoral fellows

Anja Holm

M.Sc. Molecular Biology, PhD
anja.holm.01@regionh.dk   
Curriculum Vitae 

Anja graduated in 2011 from Aarhus University where she studied molecular biology. During her master she worked at the Molecular Medicine Department, Aarhus University Hospital in Professor Torben Falck Oerntoft’s laboratory. She also worked in close collaboration with the miRNA expect Professor Jørgen Kjems, Molecular Biology Department, Aarhus University. Her main focus was in vitro expression and phenotypic characterization of clinically relevant miRNAs in colorectal cancer. She has obtained excellent results and acquired a lot of experience in various techniques of molecular biology.  Anja was awarded with a scholarship stipend from the Danish Cancer Research Foundation.

During her Ph.D. at the Danish Centre for Sleep Medicine and the Molecular Sleep Laboratory she investigated miRNAs in plasma and cerebrospinal fluid from patients with narcolepsy. She also worked at Stanford University, mentored by the world famous professor Emmanuel Mignot, where she was trained in the genetic aspects of sleep science. 

Anjas current project deals with the interaction between miRNAs and hypocretin. One of the primary aims is to investigate if an increase in miRNA levels cause sleep disorders/disturbances, such as narcolepsy, Rett Syndrome etc. 

She has been invited to present her results for several conferences, e.g. European Sleep Research Society 2012, World Congress on Sleep Medicine 2013, World Congress on Sleep Medicine 2015.  

Additionally, Anja is a member of the local Research Council at Glostrup Hospital.

Matilda Degn Vinther

matilda.degn.vinther@regionh.dk

I have a MSc in Human Biology and a PhD in neuroimmunology and pharmacology from University of Copenhagen. My graduate work focused on the role of immune modulatory endogenous cannabionoids in cerebral ischemia and importance for microglial function. 

My primary research interest is the mechanisms that initiate and maintain autoimmunity. Previous employments include positions within biotech, medical industry as well as academia and I am experienced in the development of animal models, primary cultures and master a wide range of techniques including immunoassays and in particular Flow Cytometry.

In my most recent position, I worked with Multiple Sclerosis, in particular focusing on the mechanisms involved in the recruitment of immune cells to CNS and responsible for disturbances in the balance between pro-inflammatory and regulatory cells.

The aim of my current project is to elucidate the background of the autoimmune reaction causing loss of hypocretinergic neurons in patients with Narcolepsy.  I will do this by creating an animal model of Narcolepsy that has a specific immune response against these neurons. Such a model would allow a number of important questions regarding Narcolepsy to be investigated. 

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