MD, DMSc, Senior Researcher
Steen Gammeltoft’s research, driven by an innate originality and curiosity, ranges from insulin action to cancer cell growth, neuronal survival and sleep biology.
The first 15 years of his career he researched in insulin molecular structure and function, which earned him the Medical Doctorate in 1985. The research futher led Steen Gammeltoft abroad as a visiting scientist at the University of Nice, France in 1984 and a visiting professor at Joslin Diabetes Center, Harvard Medical School, USA in 1993.
Then Steen Gammeltoft shifted focus to growth factor action on brain growth and regeneration of nerve cells. Interest in new fields of research has also led him to studies in systems biology, bioinformatics, mass spectrometry, and recently sleep research together with prominent researchers in Denmark. He has published 175 scientific articles in prestigious international journals. Steen Gammeltoft has throughout his career favored elite and excellence in research.
Biochemistry, Berlin University
Maren is a biochemistry student from Berlin, where she has been studying at Freie Universität since 2009. She will be doing her Master thesis in our group between October 2013 and April 2014. During her studies she has been to Copenhagen and Spain doing internships for her studies, apart from being an intern at different research institutes in Berlin gaining practical experiences in different fields. Her master thesis will focus on the melanine-concentrating hormone in sleep and metabolism using patient samples and cell culture.
Lars Schack Kruse
B.Sc. in biochemistry,
M.Sc. in Human Biology, Ph.D.
Lars has a strong background within neurovascular molecular biology. He did his Master’s thesis on the phospho-regulation of 3-phosphoinositide-dependent kinase-1 (PDK1) and proceeded to do a Ph.D. on cyclic nucleotide signaling in migraine with special emphasis on the distribution and activity of the phosphodiesterase (PDE) enzyme family.
During his Ph.D. he attended the lab of Professor Joseph A. Beavo, one of the founding fathers of PDE research, at Department of Pharmacology, University of Washington in Seattle.
In his most recent employment Lars worked on the vascular implications of second-hand smoking with special emphasis on stroke, acute myocardial infarction and chronic obstructive pulmonary disease in close collaboration with Center for COPD research at University of Southern Denmark and Department of Neurology, University of Szeged, Hungary.
Lars’ current project deals with metabolism of hypocretin in narcolepsy. One of the primary aims is to evaluate the validity of the currently used diagnostic kit for narcolepsy measuring serum or CSF levels of hypocretin.
Additionally, Lars is currently a member of the work environment group at Glostrup Research Institute, long-standing member of the local Research Council at Glostrup Hospital, organization-wide administrator of the regional research registration initiative PURE, chemical agent and IT Super User.
M.Sc. Biology, PhD
Currently, Kim is preforming electrophysiological in vivo in genetical modified mice, displaying a narcoleptic phenotype.
He is using electroencephalographic (EEG) and electromyographic (EMG) recordings to assess the sleep architecture of these animals. By applying mouse models of this sleep disorder he can examine the mechanistic background of sleep regulation, the interplay between sleep and the immune system, and the influence of the sleep related neuropeptides.
Kim graduated in Biology from Aarhus University where he developed in vitro models of Parkinson’s disease to evaluate electrophysiological changes in neuronal functioning. Furthermore, Kim was working at The Royal Children’s Hospital, Melbourne, Australia as part of his undergraduate studies.
He obtained his PhD degree in neuropharmacology from the University of Copenhagen, Department of Drug Design and Pharmacology. His graduate work was centred around extrasynaptic GABA(A) receptors and their therapeutic potential, which was investigated using in vivo pharmacology, electrophysiology, immunohistochemistry and recombinant expression assays. The experimental work was partly performed at the Institute of Neurology, University College London.
Human biology, University of Copehagen
Jessica graduated from the University of Texas with a Bachelor of Science in Psychology and a Bachelor of Science in Biology (with a concentration in neurobiology).
After working in Health IT for a year, Jessica received a scholarship to participate in the Human Biology Master of Excellence program at the University of Copenhagen and moved to Denmark. She began volunteering at Glostrup in the fall of 2012, looking at hypocretin expression in different cell lines.
Currently, she is investigating the effect of different sleep deprivation paradigms on hypocretin activation at the Molecular Sleep Lab and participating in the BioBusiness and Innovation Platform (BBIP) project at Copenhagen Business School.
For more information, please see http://dk.linkedin.com/pub/jessica-thomas/2b/1a8/344/
Kristine Frøsig Moseholm
University of Copenhagen
In 2011 Kristine graduated with a Bachelors degree in Biology with a special interest in Neuroscience from the University of Copenhagen. Afterwards, she worked 6 month as a research volunteer at the Unit for Cognitive Neuroscience, University of Copenhagen and as a student assistant, working with research in miRNAs at the Peter Brodersen Lab, University of Copenhagen. In 2012 Kristine was accepted as a student at the Human Biology Master of Excellence Programme, University of Copenhagen.
During her Master thesis at the Molecular Sleep Laboratory, Kristine will investigate the effects and regulations of hypocretin induced by cytokines and whether this is mediated by miRNAs.
Marc Phillip Gall Schultz Lorentzen
Mette Udengaard Nors