Publications from the Bartholin Institute

List of publications from the Bartholin Institute 2010 - 2018

2018


Hansen LBS, Roager HM, Søndertoft NB, Gøbel RJ, Kristensen M, Vallès-Colomer M, Vieira-Silva S, Ibrügger S, Lind MV, Mærkedahl RB, Bahl MI, Madsen ML, Havelund J, Falony G, Tetens I, Nielsen T, Allin KH, Frandsen HL, Hartmann B, Holst JJ, Sparholt MH, Holck J, Blennow A, Moll JM, Meyer AS, Hoppe C, Poulsen JH, Carvalho V, Sagnelli D, Dalgaard MD, Christensen AF, Lydolph MC, Ross AB, Villas-Bôas S, Brix S, Sicheritz-Pontén T, Buschard K, Linneberg A, Rumessen JJ, Ekstrøm CT, Ritz C, Kristiansen K, Nielsen HB, Vestergaard H, Færgeman NJ, Raes J, Frøkiær H, Hansen T, Lauritzen L, Gupta R, Licht TR, Pedersen O. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults. Nat Commun. 2018 Nov 13

Haupt-Jorgensen M, Morgen CS, Jess T, Buschard K, Josefsen K, Allin KH, et al. Maternal Antibiotic Use During Pregnancy and Type 1 Diabetes in Children—A National Prospective Cohort Study. Diabetes Care. 2018 Oct 16;dc181764

 
 

Holm LJ, Haupt-Jorgensen M, Larsen J, Giacobini JD, Bilgin M, Buschard K. L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice. PLoS One. 2018 Mar 15; 13(3):e0194414

Haupt-Jorgensen M, Larsen J, Josefsen K, Jørgensen TZ, Antvorskov JC, Hansen AK, Buschard K. Gluten-free diet exclusively during pregnancy alleviates the signs of diabetes and celiac disease in NOD mouse offspring. Diabetes Metab. Res. Rev. 2018 Feb 2

Theses

Martin Haupt-Jørgensen: Mechanisms of protection against diabetes by a gluten-free diet. PhD thesis.  


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2017


 
 
 
 

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2016



Antvorskov JC, Josefsen K, Haupt-Jorgensen M, Fundova P, Funda DP, Buschard K: Gluten-Free Diet Only during Pregnancy Efficiently Prevents Diabetes in NOD Mouse Offspring. J Diabetes Res. 2016;2016:3047574.


Nielsen SM, Vinther-Jensen T, Nielsen JE, Nørremølle A, Hasholt L, Hjermind LE, Josefsen K: Liver function in Huntington’s disease assessed by blood biochemical analyses in a clinical setting. J. Neurol Sci. 2016 Mar 15;362:326-32

Haupt-Jorgensen M, Buschard K, Hansen AK, Josefsen K, Antvorskov JC: Gluten-free diet increases beta-cell volume and improves glucose tolerance in an animal model of type 2 diabetes. Diabetes Metab. Res. Rev. Mar. 17

Buschard K, Bracey AW, McElroy DL, Magis AT, Osterbye T, Atkinson MA, Bailey KM, Posgai AL, Ostrov DA: Sulfatide Preserves Insulin Crystals Not by Being Intergrated in the Lattice but by Stabilizing Their Surface. J. Diabetes Res. 2016;2016:6179635.

Rune I, Rolin B, Larsen C, Nielsen DS, Kanter JE, Bornfeldt KE, Lykkesfeldt J, Buschard K, Kirk RK, Christoffersen B, Fels JJ, Josefsen K, Kihl P, Hansen AK: Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice. PLoS One. 2016 Jan 22;11(1):e0146439

Damlund DS, Metzdorff SB, Hasselby JP, Wiese M, Lundsager M, Nielsen DS, Buschard KS, Hansen AK, Frøkiær H: Postnatal Hematopoiesis and Gut Microbiota in NOD mice Deviate from C57BL/6 Mice. J. Diabetes Res. Vol  2016, Article ID: 6321980​

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2015​

Adlercreutz E, Svensson J, Hansen D, Buschard K, Lernmark Å, Mortensen H, Agardh D: Prevalence of celiac disease autoimmunity in children with type 1 diabetes: regional variations across the Øresund strait between Denmark and southernmost Sweden. Pediatr Diabetes 16: 504-509, 2015.​

Larsen J, Weile C, Antvorskov JC, Engkilde K, Nielsen SM, Josefsen K, Buschard K: Effect of Dietary Gluten on Dendritic Cells and Innate Immune Subsets in BALB/c and NOD Mice. PLoS One. 2015;10(3). doi:10.1371/journal.pone.0118618

Fjelbye J, Antvorskov JC, Buschard K, Issazadeh-Navikas S, Engkilde K: CD1d knockout mice exhibit aggravated contact hypersensitivity responses due to reduced interleukin-10 production predominantly by regulatory B cells. Exp Dermatol 11: 853-856, 2015.

Antvorskov JC, Buschard K, Josefsen K. Pathogenesis of type 1 diabetes: Role of dietary factors. In: Molecular nutrition and diabetes 51-62, 2015. Elsevier, Ed: D Mauricio.

Nielsen SM, Hasholt L, Nørremølle A, Josefsen K. Progressive Impairment of Lactate-based Gluconeogenesis in the Huntington’s Disease Mouse Model R6/2. PLoS Curr. 2015 Apr 20;7. doi: 10.1371/currents.hd.019b33aae1c519e6e8b68e7cf3e7818e.​​

Larsen J, Weile C, Antvorskov JC, Engkilde K, Nielsen SM, Josefsen K, Buschard K. Effects of dietary gluten on dendritic cells and innate immune subsets in BALB/c and NOD mice. PLoS One. 2015 Mar 4;10(3):e0118618

Theses

Dina Silke Malling Damlund: Early life hematopoiesis in non-obese diabetic mice. PhD thesis.

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​2014

Wheat has been shown to play a major role in the development in noth animal models and T1D in humans.

Adlercreutz EH1, Weile C, Larsen J, Engkilde K, Agardh D, Buschard K, Antvorskov JC. A gluten-free diet lowers NKG2D and ligand expression in BALB/c and non-obese diabetic (NOD) mice. Clin Exp Immunol. 2014 Aug;177(2):391-403.

Adlercreutz EH, Svensson J, Hansen D, Buschard K, Lernmark A, Mortensen HB, Agardh D. Prevalence of celiac disease autoimmunity in children with type 1 diabetes: regional variations across the Øresund strait between Denmark and southernmost Sweden. Pediatr Diabetes. 2014 Aug 18.

Larsen J, Dall M, Antvorskov JC, Weile C, Engkilde K, Josefsen K, Buschard K. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014 Oct;44(10):3056-67.

Hansen CH, Andersen LS, Krych L, Metzdorff SB, Hasselby JP, Skov S, Nielsen DS, Buschard K, Hansen LH, Hansen AK. Mode of delivery shapes gut colonization pattern and modulates regulatory immunity in mice. J Immunol. 2014 Aug 1;193(3):1213-22.

Antvorskov JC, Josefsen K, Engkilde K, Funda DP, Buschard K. Dietary gluten and the development of type 1 diabetes. Diabetologia. 2014 Sep;57(9):1770-80.

Nielsen DS, Krych L, Buschard K, Hansen CH, Hansen AK. Beyond genetics. Influence of dietary factors and gut microbiota on type 1 diabetes. FEBS Lett. 2014 Apr 18

Funda DP, Fundova P, Hansen AK, Buschard K. Prevention or early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice. PLoS One. 2014 Apr 11;9(4):e94530.

Hansen CH, Krych L, Buschard K, Metzdorff SB, Nellemann C, Hansen LH, Nielsen DS, Frøkiær H, Skov S, Hansen AK. A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice. Diabetes. 2014 Aug;63(8):2821-32.

Pyndt Jørgensen B, Hansen JT, Krych L, Larsen C, Klein AB, Nielsen DS, Josefsen K, Hansen AK, Sørensen DB. A possible link between food and mood: dietary impact on gut microbiota and behavior in BALB/c mice. PLoS One. 2014 Aug 18;9(8):e103398.

Sørensen JO, Buschard K, Brogren CH: The preventive role of type 2 NKT cells in the development of type 1 diabetes. APMIS 122: 167-182. 2014.

Svalgaard JD, Særmark C, Dall M, Buschard K, Johansen JD, Engkilde K: Systemic immunogenicity of para-phenylenediamine and diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunol Res. 58: 40-50, 2014.

Adlercreutz EH, Hansen D, Mortensen HB, Lernmark Å, Buschard K, Agardh D, Svensson J: Risk of celiac disease autoimmunity is modified by non-HLA genetic markers during the first year of clinical type 1 diabetes. J Diabetes Endocrinology. 2: 58-64, 2014.

Engkilde K, Kihl P, Thyssen JP, Stegenborg-Jensen G, Buschard K, Menné T, Linneberg A, Johansen JD, Hansen AK: Does Contact Allergy Affect the Risk of Type 2 Diabetes? Plos One, under revision.

Antvorskov JC, Aunsholt L, Gamborg M, Buschard K, Kristensen K, Johannesen J, Sørensen TIA, Svensson J: Childhood BMI and the risk of type 1 diabetes. Submitted.

Bruun SW, Josefsen K, Tanassi JT, Marek A, PedersenMH, Sidenius U, Haupt-Jorgensen M, Antvorskov JC, Heegaard NH, Buschard K: Gliadin fragments in mouse blood and pancreas after oral administration. Submitted.

Theses

Emma Adlercreutz: The Perfect Storm? Gluten and type 1 diabetes. Med.dr. thesis.

Jesper Larsen: NK cells and gliadin in the development of type 1 diabetes. PhD thesis.

Mia Kolbjørn Melgaard: 2′,5′-oligoadenylate synthetase activity in beta-cells and beta-cell lines, measured by fluorometry and separation by thin layer chromatography. Master thesis.

Noor Al-Shamary: Noninvasive Imaging of the pancreatic beta-cell mass using fragments and engineered formats of the monoclonal autoantibody, IC2 – Comparative studies by Near-Infrared and Positron Emission Tomography Imaging. Master Thesis.

Amila Kapicic: Identification and characterization of the monoclonal IC2 autoantibody targeted plasma membrane lipids by hyphenated HPTLC DESI-Mass Spectrometry. Master thesis.

Christina Petersen Engmose: The role of immune regulatory NKT cells in T1D and their inhibition by the monoclonal autoantibody IC2. Master thesis. Submitted.

Signe Marie Borch Nielsen: Aspects of hepatic metabolic dysfunction in Huntington´s disease. PhD thesis. Submitted

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2013

Svalgaard JD, Særmark C, Dall M, Buschard K, Johansen JD, Engkilde K. Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunol Res. 2014 Jan;58(1):40-50. doi: 10.1007/s12026-013-8482-z.

Sørensen JO, Buschard K, Brogren CH. The preventive role of type 2 NKT cells in the development of type 1 diabetes. APMIS. 2013 Aug 29. doi: 10.1111/apm.12140.

Dall M, Calloe K, Haupt-Jorgensen M, Larsen J, Schmitt N, Josefsen K, Buschard K. Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans.
PLoS One. 2013 Jun 13;8(6):e66474.

Rune I, Hansen CH, Ellekilde M, Nielsen DS, Skovgaard K, Rolin BC, Lykkesfeldt J,Josefsen K, Tranberg B, Kihl P, Hansen AK. Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent. J Diabetes Res. 2013;2013:319321.

Theses

Mie Sefeld : Fremstilling og evaluering af nær-infrarøde fluorescente konjugater og guld nanorods konjugater af IC2 autoantistoffet og dets fragmenter til anvendelse i NIR og PAT noninvasiv imaging af pankreas beta-celler

Ida Dalgaard Pedersen : Investigation of the structural epitope recognized by the beta-cell specific monoclonal autoantibody IC2

Katrine Louise Jensen : Development and characterization of syngeneic monoclonal anti-idiotypic antibodies to the monoclonal beta-cell specific antibody IC2

Martin Haupt-Jørgensen: Effect of a gluten-free diet on incidence and inflammation in an animal model of type 2 diabetes

Morten Dall: Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans

Lisa Blanch Folmann: Investigation of Metabolism and transscriptional dysregulation in the Huntington´s disease mouse model R6/2

Laura Dall Køhler: Immunological and Metabolic Changes in Huntington´s Disease Liver: Effect of Cytokines on Gluconeogenesi

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2012

Weile C: Identification of antigen-related autoantigen in type 1 diabetes mellitus. PhD thesis PhD_thesis_Christian_weile.pdfArigi E, Blixt O, Buschard K, Clausen H, Levery SB: Design of a covalently bonded glycosphingolipid microarray. Glycoconjugate Journal 29: 1-12, 2012.

Kaas A, Andersen MLM, Fredheim S, Hougaard P, Buschard K, Petersen JS, de Beaufort C, Robertson KJ, Hansen L, Mortensen HB, Nielsen LB: Proinsulin, GLP-1 and Glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes. Pediatr Diabetes 13:51-58, 2012.

Kaas A, Pfleger C, Kharagjitsingh AV, Schloot NC, Hansen L, Buschard K, KoelemanBPC, Roep BO, Mortensen HB, Alizadeh BZ: Association between age, IL-10, IFNγ, stimulated C-peptide and disease progression in children with newly diagnosed type 1 diabetes. Diabetic Med 6: 734-741, 2012.

Antvorskov J, Fundova P, Buschard K, Funda D: Impact of Dietary Gluten on Regulatory T Cells and Th17 Cells in BALB/c Mice. PloS One 7(3):e33315, 2012.

Hansen CHF, Krych L, Nielsen DS, Vogensen FK, Hansen LH, Sørensen SJ, Buschard K, Hansen AK: Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in non-obese diabetic (NOD) mice. Diabetologia 55: 2285-2294, 2012.

Subramanian L, Blumenfeld H, Tohn R, Ly D, Aguilera C, Maricic I, Mansson J-E, Buschard K, Kumar V, Delovitch TL: NKT cells stimulated by long fatty acyl chain sulfatides significantly reduce the incidence of Type 1 Diabetes in Nonobese Diabetic Mice. Plos One PLoS One. 2012;7(5):e37771.

Sildorf SM, Fredheim S, Svensson J, Buschard, K: Remission without insulin therapy on gluten-free diet in a six-year old boy with type 1 diabetes. BMJ Case Rep. 2012 pii: bcr0220125878. doi: 10.1136/bcr.02.2012.5878.

Antvorskov JC, Fundova P, Buschard K, Funda DP: Dietary gluten alters the balance of proinflammatory and anti-inflammatory cytokines in T cells of BALB/c mice. Immunology,

Ladefoged M, Buschard K, Hansen AM: Increased expression of TLR4 and inflammatory cytokines, IL-6 in particular, in islets from a mouse model of obesity and type 2 diabetes. APMIS, 

Buschard K, Månsson J-E, Roep BO, Nikolic T: Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells. Plos One

Lundberg R, Clausen SK, Pang W, Nielsen DS, Möller K, Josefsen KE, Hansen AK. Gastrointestinal Microbiota and Local Inflammation during Oxazolone-induced Dermatitis in BALB/cA Mice. Comp Med. 2012;62(5):371-80.

Bangsgaard Bendtsen KM, Krych L, Sørensen DB, Pang W, Nielsen DS, Josefsen K, Hansen LH, Sørensen SJ, , Hansen AK. Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse. PLoS One. 2012;7(10):e46231. Epub 2012 Oct 2.

Minocherhomji S, Seemann S, Mang Y, El-Schich Z, Bak M, Hansen C, Papadopoulos N, Josefsen K, Nielsen H, Gorodkin J, Tommerup N, Silahtaroglu A. Sequence and expression analysis of gaps in human chromosome 20. Nucleic Acids Res. 2012 Aug;40(14):6660-72. Epub 2012 Apr 17.


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2011

Weile C, Josefsen K, Buschard K. Glucose activation of islets of Langerhans up-regulates Toll-like receptor 5: possible mechanism of protection. Clin Exp Immunol. 2011 Nov;166(2):251-7. doi: 10.1111/j.1365-2249.2011.04457.x.

Stefkov G, Kulevanova S, Miova B, Dinevska-Kjovkarovska S, Mølgaard P, Jäger AK, Josefsen K. Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. Pharm Biol. 2011 Sep;49(9):885-92. doi: 10.3109/13880209.2011.552187. Epub 2011 May 27.

Josefsen K, Lee YC. Validation of RNAi by real time PCR. Methods Mol Biol. 2011;703:205-17. doi: 10.1007/978-1-59745-248-9_14.

Josefsen K, Nielsen H. Northern blotting analysis. Methods Mol Biol. 2011;703:87-105. doi: 10.1007/978-1-59745-248-9_7.

Campbell-Tofte JI, Mølgaard P, Josefsen K, Abdallah Z, Hansen SH, Cornett C, Mu H, Richter EA, Petersen HW, Nørregaard JC, Winther K. Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine.J Ethnopharmacol. 2011 Jan 27;133(2):402-11. doi: 10.1016/j.jep.2010.10.013. Epub 2010 Oct 16.

Kaas A, Andersen ML, Fredheim S, Hougaard P, Buschard K, Petersen JS, de Beaufort C, Robertson KJ, Hansen L, Mortensen HB, Nielsen LB Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes. Pediatr Diabetes. 2012 Feb;13(1):51-8. doi: 10.1111/j.1399-5448.2011.00812.x. Epub 2011 Nov 27.

Arigi E, Blixt O, Buschard K, Clausen H, Levery SB. Design of a covalently bonded glycosphingolipid microarray. Glycoconj J. 2012 Jan;29(1):1-12. doi: 10.1007/s10719-011-9359-9. Epub 2011 Nov 22.

Engkilde K, Johansen JD, Hansen AK, Menné T, Buschard K. Prevention of type 1 diabetes by inducing subclinical dermatitis on a small area. Diabetes Metab Res Rev. 2011 Nov;27(8):954-8. doi: 10.1002/dmrr.1280.

Weile C, Josefsen K, Buschard K. Glucose activation of islets of Langerhans up-regulates Toll-like receptor 5: possible mechanism of protection. Clin Exp Immunol. 2011 Nov;166(2):251-7. doi: 10.1111/j.1365-2249.2011.04457.x.

Buschard K. What causes type 1 diabetes? Lessons from animal models. APMIS Suppl. 2011 Jul;(132):1-19. doi: 10.1111/j.1600-0463.2011.02765.x. Review.

Buschard K, Hansen AK, Jensen K, Lindenbergh-Kortleve DJ, de Ruiter LF, Krohn TC, Hufeldt MR, Vogensen FK, Aasted B, Osterbye T, Roep BO, de Haar C, Nieuwenhuis EE. Alcohol facilitates CD1d loading, subsequent activation of NKT cells, and reduces the incidence of diabetes in NOD mice. PLoS One. 2011 Apr 1;6(4):e17931. doi: 10.1371/journal.pone.0017931.

Cardwell CR, Stene LC, Joner G, Bulsara MK, Cinek O, Rosenbauer J, Ludvigsson J, Svensson J, Goldacre MJ, Waldhoer T, Jarosz-Chobot P, Gimeno SG, Chuang LM, Roberts CL, Parslow RC, Wadsworth EJ, Chetwynd A, Brigis G, Urbonaite B, Sipetic S, Schober E, Devoti G, Ionescu-Tirgoviste C, de Beaufort CE, Stoyanov D, Buschard K, Radon K, Glatthaar C, Patterson CC. Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies. Int J Epidemiol. 2011 Apr;40(2):363-74. doi: 10.1093/ije/dyq207. Epub 2010 Dec 10. Review.

Master and Phd-theses

Borch Nielsen S. Reduced hepatic gluconeogenesis and systemic lactate clearance in the Huntington’s disease R6/2 mouse model.

​Dall M. Etablering af en in vitro-model til belysning af insulinresistens.

Iv​ersen L. Transcription factors in the liver of the R6/2 mouse model.

Køhler L. Liver function in huntingtin-transfected mouse liver.

Weile C. Identifikation af antigener involveret i patogenesen af type 1 diabetes mellitus (T1DM) i de insulinproducerende betaceller.

Antvorskov J.C.,”Dietary gluten and type 1 diabetes”. PhD thesis. Faculty of Health Sciences. (Ph.D Thesis)

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20​10

Cardwell CR, Stene LC, Joner G, Bulsara MK, Cinek O, Rosenbauer J, Ludvigsson J, Jané M, Svensson J, Goldacre MJ, Waldhoer T, Jarosz-Chobot P, Gimeno SG, Chuang LM, Parslow RC, Wadsworth EJ, Chetwynd A, Pozzilli P, Brigis G, Urbonaite B, Sipetic S, Schober E, Devoti G, Ionescu-Tirgoviste C, de Beaufort CE, Stoyanov D, Buschard K, Patterson CC: Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies. Diabetes 59: 486-494, 2010.

Cardwell CR, Stene LC, Joner G, Davis EA, Cinek O, Rosenbauer J, Ludvigsson J, Castell C, Svensson J, Goldacre MJ, Waldhoer T, Polanska J, Gimeno SG, Chuang LM, Parslow RC, Wadsworth EJ, Chetwynd A, Pozzilli P, Brigis G, Urbonaitė B, Sipetić S, Schober E, Ionescu-Tirgoviste C, de Beaufort CE, Stoyanov D, Buschard K, Patterson CC: Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data. Diabetologia. Diabetologia.53: 641-651, 2010.

Buschard K :Sulphated galactosylceramide. Diabetologia. 53: 1007-1008, 2010.

Engkilde K, Buschard K, Hansen AK, Menné T, Johansen JD: Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis. Plos One 5(5):e10591, 2010.

Kaas A, Pfleger C, Hansen L, Buschard K, Schloot NC, Roep BO, Mortensen HB: Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis. Clin Exp Immunol 161: 444-452, 2010.

Lauritsen LFS, Hufeldt MR, Aasted B, Hansen CHF, Midtvedt T, Buschard K, Hansen AK: The Impact of a Germ Free Perinatal Period on the Variation in Animal Models of Human Inflammatory Diseases - A Review. Scand J Lab Animal Science 37: 43-54, 2010.

Roeske-Nielsen A, Dalgaard LT, Mansson J-E, Buschard K: Sulfatide protects insulin-producing cells against a cytokine-induced apoptosis, a possible role in diabetes. Diabetes Metab Res Rev 26: 631-638, 2010.

Osterbye T, Funda DP, Fundová P, Månsson J-E, Tlaskalová-Hogenová H,Buschard K: A subset of human β-cells expresses functional CD14 receptor: a signaling pathway for β-cell-related glycolipids, sulfatide and β-galactosylceramide. Diabetes Metab Res Rev 26: 656-67, 2010.

Josefsen K, Lee YC, Thams P, Efendic S, Nielsen JH. FEBS Letters. AKAP 18 alfa and γ have opposing effects on insulin release in INS 1E cells. 2010;584:81-5.

Josefsen K, Nielsen SM, Campos A, Seifert T, Hasholt L, Nielsen JE, Nørremølle A, Skotte NH, Secher NH, Quistorff B. Reduced gluconeogenesis and lactate clearance in Huntington's disease. Neurobiol Dis. 2010;40:656-62.



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