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Research

Our research is focused at identification and implementation of new cancer biomarkers, identification and characterization of novel targets for future cancer treatment and identification of molecular mechanisms underlying the behaviour of cancer stem cells as well as their normal counterparts. We currently house 6 research groups working on projects relevant for cancer.

Behrendt Group

The group has its focus on the mechanisms of cellular invasion and on novel means of cancer treatment, developed through the targeting of cellular components involved in cancer invasion. In particular, we study the processes of extracellular matrix degradation through proteolytic and endocytic mechanisms and the utilization of the responsible molecular components for targeted drug delivery.

26. August 2020 / 22:59

Engelholm Group

The main focus area in this research group is collagen turnover in pathological and physiological conditions in mammals. We try to elucidate some of the mechanisms behind dysregulated collagen homeostasis in cancer and several other pathological diseases with either collagen accumulation (fibrosis) or excess collagen degradation (e.g. osteoporosis).

26. August 2020 / 22:59

Ploug Group

Our research is focused on structural and functional aspects of proteins involved in cellular invasion and matrix degradation. The ultimate goal of these studies is to elucidate the function of these proteins in vitro and in vivo and to facilitate the translation of these findings into a clinical setting, particularly within the field of oncology.

26. August 2020 / 22:59

Porse Group

Cancer is a devasting disease targeting millions of people world-wide. In order to develop normal targeted therapies to combat cancer we need detailed understanding of the molecular mechanisms governing both the initiation and maintenance of cancer. Furthermore, to forward novel candidate targets for future drug development we also need to understand their function in the corresponding normal tissues.

26. August 2020 / 22:59

Theilgaard-Mönch Group

The major focus of the Theilgaard-Mönch group is to compare cancer cells to their closest normal cellular counterpart using a variety of omics technologies in order to improve prognostication as well as identify novel targets for treatment of patients with acute myeloid leukaemia (AML).

26. August 2020 / 22:59

Weischenfeldt Group

Cancer is a genetic disease and is caused by accumulation of genomic alterations that improve the fitness of the cell. We utilize cancer genomics approaches to characterize the mechanisms, functional consequences and prognostic relevance of genomic alterations in cancer.

26. August 2020 / 22:59

Publishing date: 2/3/2017 11:01 AM