Research at the Department of Intensive Care

The focus of the research program at The Intensive Care Unit (ICU) is the critically ill patient. ​


Clinical and pathophysiological questions are assessed through clinical databases, pathophysiological studies of patients and experimental studies of critical diseases.

The research unit collaborates with several local, national and international organisations, including all of the ICUs in the Capital Region of Denmark, several other Danish and Scandinavian ICUs and the George Institute of International Health, University of Sydney.

Current projects

The 5-year strategic research programme ‘New resuscitation strategies in severe sepsis’ The program includes 3 large multicenter RCTs on fluid therapy (the 6S trial) and blood (the TRISS trial) in patients with sepsis. The research programme is funded by the Danish Strategic Research Council.

Pathophysiological studies on pulmonary inflammation and cerebral autoregulation The unit is in collaboration with the Center for Inflammation and Metabolism.

EAT ICU – an interventional study investigating the effect of early goal directed nutrition to critically ill patients.

SUP-ICU - a research programme assessing stress ulcers and proton pump inhibitors in ICU-patients.
Pharmacokinetic studies of antibiotics.

Patophysiological and observational studies of patients with necrotizing fasciitis.
Qualitative and quantitative assessments of quality of life in patients after ICU discharge.

Research staff

Head of the research unit
Anders Perner, professor, PhD., EDIC

  • 7 PhD. Students​​
  • 5 research nurses 
  • A varying number of medical students

Statistical Analysis Plan - post-hoc analyses of bleeding and transfusion in the 6S-trial​

Responsible editor