Forskningspublikationer

​De seneste års forskningspublikationer fra Epilepsiklinikken. 

​Publikationer 2014

Feng L, Svarer C, Thomsen G, de Nijs R, Larsen VA, Jensen P, Adamsen D, Dyssegaard A, Fischer W, Meden P, Krieger D, Møller K, Knudsen GM, Pinborg LH (2014) In Vivo Quantification of Cerebral TSPO Binding in Humans using [123I]CLINDE SPECT. Accepted for publication in Journal of Nuclear Medicine

Hansen FH, Skjørringe T, Yasmeen S, Arends NV, Sahai MA, Erreger K, Andreassen TF, Holy M, Hamilton PJ, Neergheen V, Karlsborg M, Newman, AH, Pope S, Heales SJR, Friberg L, Law I, Pinborg LH, Sitte HH, Loland C, Shi L, Weinstein H, Galli A, Hjermind LE, Gether U (2014) Missense mutations in the dopamine transporter gene associate with adult parkinsonism and ADHD. J Clin Invest 124(7):3107-20

Jørgensen A, Hansen BS, Stanislaus S, Düring S, Jørgensen MB, Pinborg LH, Kondziella D (2014) Anti-NMDA receptor encephalitis is an important differential diagnosis in acute psychiatric disease. Accepted for publication in Acta Psychiatrica Scandinavica

Jensen P, Kondziella D, Thomsen G, Dyssegaard A, Svarer C, Pinborg LH (2014) Anti-NMDAR encephalitis: demonstration of neuroinflammation and the effect of immunotherapy. Accepted for publication in Neurology

Kaalund SS, Venø MT, Bak M, Møller RS, Laursen H, Madsen FF, Broholm H, Quistorff B, Uldall P, Tommerup N, Kauppinen S, Sabers A, Fluiter K, Møller LB, Nossent AY, Silahtaroglu A, Kjems J, Aronica E, Turmer Z. (2014) Aberant axpression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal Sclerosis-Convergence on axonal guidance.  Epilepsia, 55(12); 2017-2027

Mosbech MB, Olsen AS, Neess D, Ben-David O, Klitten L, Larsen J, Sabers A, Vissing J, Nielsen J, Hasholt L, Klein A, Tsoory M, Hjalgrim H, Tommerup N, Futerman A, Møller R, Færgeman RN. (2014) Reduced Ceramide Synthase 2 Activity Causes Progressive Myoclonic Epilepsy.  Annals of Clinical and Translational Neurology,  1(2): 88-98

Sabers A, Scheel-Kruger J, Nyengaard J, Bertelsen F, Møller A. (2014) Valproic acid increases neurons in the developing rat brain. A possible animal model of autism. Neuroscience Letters, 580; 12-16

Wulff S, Pinborg LH, Svarer C, Jensen LT, Nielsen MØ, Allerup P, Bak N, Rasmussen H, Frandsen E, Rostrup Y, Glenthøj BY (2014). Striatal D2/3 Binding Potential Values in Drug-Naïve First-Episode Schizophrenia Patients Correlate with Treatment Outcome. Accepted for publication in Schizophrenia Bulletin​​​

Publikationer 2013

Battino D, Tomson T, Bonizzoni E, Craig J, Lindhout D, Sabers A, Perucca E, Vajda F. (2013) EURAP Study Group. Seizure Control and Treatment Changes in Pregnancy: Observations from the EURAP Epilepsy Pregnancy Registry. Epilepsia, 54(9):1621-1627

Benicsky S, Lantz G, Rosenzweig I, Åkeson P, Pedersen B, Pinborg LH, Ziebell M, Jespersen B, Fuglsang-Frederiksen A. (2013) Source localization of rhytmic ictal EEG activity: A study of diagnostic accuracy following STARD criteria. Epilepsia 54(10):1743-52

Holst AG, Winkel BG, Risgaard B, Nielsen, Rasmussen PV, Haunsø S, Sabers A, Uldall P, Tfelt-Hansen J. (2013) Epilepsy and the risk of death and sudden unexpected death: A nationwide study, Epilepsia, 54(9):1613-1620

Jacobs AH, Tavitian B, the INMiND consortium. 2012. Noinvasive molecular imaging og neuroinflammation. J Cereb Blood Flow Metab 32(7): 1393-1415

Kjær TW, Sabers A. (2013) Landsdækkende telemedicinsk hjernemonitorering. Ugeskrift for læger, 175,772

Lindquist S, Duno M, Batbayli M, Puschmann A, Braendgaard H, Mardosiene S, Svenstrup K, Pinborg L, Vestergaard K, Hjermind L, Stokholm J, Andersen B, Johannsen P, Nielsen J. 2013. Corticobasal and ataxia syndromes widen the spectrum of C9ORF72 hexanucleotide expansion disease. Clin Genet 83(3): 279-283

Pinborg LH, Feng L, Haahr ME, Gillings N, Dyssegaard A, Madsen J, Svarer C, Yndgaard S, Kjaer TW, Parsey RV, Hansen HD, Ettrup A, Paulson OB, Knudsen GM. 2012. No change in [(11) C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human. Synapse 66(10): 880-4

Rasmussen H, Ebdrup BH, Erritzoe D, Aggernaes B, Oranje B, Kalbitzer J, Pinborg LH, Baaré WF, Svarer C, Lublin H, Knudsen GM, Glenthoj B.(2013) Norquetiapine and depressive symptoms in initially antipsychotic naïve first-episode schizophrenia. J Clin Psychopharmacol 33(2): 266-269

Rasmussen H, Ebdrup BH, Oranje B, Pinborg LH, Knudsen GM, Glenthøj B (2014) Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients. Int J Neuropsychopharmacol 15:1-7

Sabers A. Treatment guidelines: Women of fertile age. Epileptology, 2013;1(1)11-16

Sabers A, Kjær TW. (2013) Epilepsi. Klinisk praksis. Ugeskrift for læger  23(176):26

Sabers A, Wolf P, Møller A, Rysgaard K, Ben-Menachem E. (2013) A prospective, randomized, multicenter trial for the treatment of refractory status epilepticus; experiences from evaluating the effect of a novel drug candidate NS1209.  Epilepsy Res 106(1-2);192-196

Thomsen G, Knudsen GM, Jensen PS, Ziebell M, Holst KK, Asenbaum S, Booij J, Darcourt J, Dickson JC, Kapucu OL, Nobili F, Sabri O, Sera T, Tatsch K, Tossici-Bolt L, Van Laere K, Borght TV, Varrone A, Pagani M, Pinborg LH. (2013) No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT. EJNMMI Res. 3(39):1-7

Thomsen G, Ziebell M, Jensen P.E., Knudsen G.M., Pinborg LH (2013) No correlation between body mass index and striatal dopamine transporter availability in healthy volunteers using SPECT and [123I]PE2I. Obesity 21(9):1803-6

Thygesen K, Sabers A. (2013) Promising effect of vagal nerve stimulation in Danish patients with epilepsy. Dan Med J. 60(3): A4597 

Ziebell M, Andersen BB, Pinborg LH, Knudsen GM, Stokholm J, Thomsen G, Karlsborg M, Høgh P, Mørk ML, Hasselbalch S (2013) Striatal dopamine transporter binding does not correlate to clinical severity in Dementia with Lewy Bodies. J Nuclear Med. 54(7):1072-6

Publikationer 2012

Eiberg H, Hansen L, Korbo L, Nielsen I, Svenstrup K, Bech S, Pinborg L, Friberg L, Hjermind L, Olsen O, Nielsen J. (2012) Novel mutation in ATP13A2 widens the spectrum of Kufor-Rakeb syndrome (PARK9). Clin Genet. 82(3): 256-263

Fagerlund B, Pinborg LH, Mortensen EL, Friberg L, Baaré WF, Gade A, Svarer C, Glenthøj BY. (2012) Relationship of frontal D2/3 binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients. Int J Neuropsychopharmacol. 17:1-14.

Howard RS, Holmes PA, Siddiqui A, Treacher D, Tsiropoulos I, Koutroumanidis M. Hypoxic-ischaemic brain injury: imaging and neurophysiology abnormalities related to outcome. QJM 2012;105:551-61.

Sabers. A. Algorithm for lamotrigine treatment before, during and after pregnancy. (2012) Acta Neurol Scand.126(1) e.1-4.

Ziebell M, Andersen BB, Thomsen G, Pinborg LH, Karlsborg M, Hasselbalch SG, Knudsen GM. (2012) Predictive value of dopamine transporter SPECT imaging with [¹²³I]PE2I in patients with subtle parkinsonian symptoms. Eur J Nucl Med Mol Imaging. 39(2):242-50. 

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