Videnskabelige publikationer 2016

​Oversigt over afdelingens artikler og bogkapitler trykt i 2016.

Ph.d afhandlinger

Bacteriology and treatment of infections in the upper and lower airways in patients with primary ciliary dyskinesia: adressing the paranasal sinuses
Alanin, M. C. 2016 Faculty of Health and Medical Sciences, University of Copenhagen.

Resistance in human pathogenic yeasts and filamentous fungi: prevalence, underlying molecular mechanisms and link to the use of antifungals in humans and the environment
Jensen, R. H. 2016 Faculty of Health and Medical Sciences, University of Copenhagen. 96 s.

Urinary Tract infections; Bacteriological, Immunological and Clinical factors in the elderly
Leihof , R. F. 2016 Aarhus University. 49 s.

The evolution and adaption of clinical Pseudomonas aeruginosa isolates from early cystic fibrosis infections
Lindegaard, M. 2016 Novo Nordisk Foundation Centre for Biosustainability, Technical University of Denmark.

The impact of anti-Pseudomonas aerugiosa lgY antibodies on phagocytic cell activity
Thomsen, K. 2016 Faculty of Health and Medical Sciences, University of Copenhagen.

Videnskabelige Artikler

Sinus surgery postpones chronic Gram-negative lung infection: cohort study of 106 patients with cystic fibrosis
Alanin, M. C., Aanaes, K., Høiby, N., Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, H. K. & von Buchwald, C. sep. 2016 I : Rhinology. 54, 3, s. 206-13 8 s.

Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
Alatraktchi, F. A., Andersen, S. B., Johansen, H. K., Molin, S. & Svendsen, W. E. 19 mar. 2016 I : Sensors. 16, 3, s. E408

Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections
Alatraktchi, F. A., Johansen, H. K., Molin, S. & Svendsen, W. E. aug. 2016 I : Nanomedicine (London, England). 11, 16, s. 2185-95 11 s.

Hvor meget skal der screenes for MRSA?
Andersen, L. P. 2 maj 2016 I : Ugeskrift for laeger. 178, 18, s. V68109

Parity and 11-Year Serum Thyrotropin and Thyroid Autoantibody Change: A Longitudinal Population-Based Study
Bjergved, L., Carlé, A., Jørgensen, T., Perrild, H., Laurberg, P., Krejbjerg, A., Ovesen, L., Bülow Pedersen, I., Rasmussen, L. B. & Knudsen, N. 25 jan. 2016 I : Thyroid : official journal of the American Thyroid Association.

Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model
Cao, B., Christophersen, L., Mette, K., Jensen, P. Ø., Sneppen, K., Høiby, N., Moser, C. & Sams, T. 2016 I : P L o S One. 11, 4, s. e0153616

Evaluation of the enterovirus laboratory surveillance system in Denmark, 2010 to 2013
Condell, O., Midgley, S., Christiansen, C. B., Chen, M., Chen Nielsen, X., Ellermann-Eriksen, S., Mølvadgaard, M., Schønning, K., Vermedal Hoegh, S., Andersen, P. H., Voldstedlund, M. & Kølsen Fischer, T. 5 maj 2016 I : Eurosurveillance (Online Edition). 21, 18

Automated surveillance system for hospital-acquired urinary tract infections in Denmark
Condell, O., Gubbels, S., Nielsen, J., Espenhain, L., Frimodt-Møller, N., Engberg, J., Møller, J. K., Ellermann-Eriksen, S., Schønheyder, H. C., Voldstedlund, M., Mølbak, K. & Kristensen, B. jul. 2016 I : The Journal of hospital infection. 93, 3, s. 290-6 7 s.

Corrigendum to 'Automated surveillance system for hospital-acquired urinary tract infections in Denmark' [Journal of Hospital Infection 93 (2016) 290-296]
Condell, O., Gubbels, S., Nielsen, J., Espenhain, L., Frimodt-Møller, N., Engberg, J., Møller, J. K., Ellermann-Eriksen, S., Schønheyder, H. C., Voldstedlund, M., Mølbak, K. & Kristensen, B. dec. 2016 . (The Journal of hospital infection).

Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice
Damlund, D. S. M., Christophersen, L., Jensen, P. Ø., Alhede, M., Høiby, N. & Moser, C. jun. 2016 I : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 124, 6, s. 500-7 8 s.

Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria
DellaValle, B., Hempel, C., Staalsoe, T., Johansen, F. F. & Kurtzhals, J. A. L. 24 aug. 2016 I : Malaria Journal. 15, 1, s. 427

Performance of Interferon-Gamma and IP-10 Release Assays for Diagnosing Latent Tuberculosis Infections in Patients with Concurrent Malaria in Tanzania
Drabe, C. H., Vestergaard, L. S., Helleberg, M., Nyagonde, N., Rose, M. V., Francis, F., Theilgaard, O. P., Asbjørn, J., Amos, B., Bygbjerg, I. C., Ruhwald, M. & Ravn, P. 2016 I : The American journal of tropical medicine and hygiene. s. 728-35

Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 - a rapid epidemiological and virological assessment
Emborg, H. D., Krause, T. G., Nielsen, L., Thomsen, M. K., Christiansen, C. B., Skov, M. N., Nielsen, X. C., Weinreich, L. S., Fischer, T. K., Rønn, J. & Trebbien, R. 2016 I : Eurosurveillance. 21, 14, s. 30189

Pre-adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates
Friman, V-P., Soanes-Brown, D., Sierocinski, P., Molin, S., Johansen, H. K., Merabishvili, M., Pirnay, J-P., De Vos, D. & Buckling, A. jan. 2016 I : Molecular Biology and Evolution. 29, 1, s. 188-98 11 s.

Dansk antibiotikapolitik gennem tiderne
Frimodt-Møller, N. 2016 I : Bibliotek for Læger. 208, 4, s. 416-424

Endothelial Glycocalyx: Shedding Light on Malaria Pathogenesis
Hempel, C., Pasini, E. M. & Kurtzhals, J. A. L. jun. 2016 I : Trends in Molecular Medicine. 22, 6, s. 453-7 5 s.

OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model
Hengzhuang, W., Song, Z., Ciofu, O., Onsøyen, E., Rye, P. D. & Høiby, N. maj 2016 I : Antimicrobial Agents and Chemotherapy. 60, 5, s. 2620-6 7 s.

"Population structure of drug-susceptible,-resistant and ESBL-producing Escherichia coli from community-acquired urinary tract"
Hertz, F. B., Nielsen, J. B., Schønning, K., Littauer, P., Knudsen, J. D., Løbner-Olesen, A. & Frimodt-Møller, N. apr. 2016 I : BMC Microbiology. 16, 63, s. 63

Erratum to: Population structure of Drug-Susceptible,-Resistant and ESBL-producing Escherichia coli from community-acquired urinary tract infections
Hertz, F. B., Nielsen, J. B., Schønning, K., Littauer, P., Knudsen, J. D., Løbner-Olesen, A. & Frimodt-Møller, N. 20 jun. 2016 . (B M C Microbiology).

Characterization of a novel blaIMP gene, blaIMP-58, using whole genome sequencing in a Pseudomonas putida isolate detected in Denmark
Holmgaard, D. B., Hansen, F., Hasman, H., Justesen, U. S. & Hammerum, A. M. jan. 2017 I : Diagnostic Microbiology and Infectious Disease. 87, 1, s. 68-70 3 s.

Orm i toilettet
Hviid, L., Møller-Bisgaard, S. & Kurtzhals, J. 15 feb. 2016 I : Ugeskrift for laeger. 178, 7, s. V67428

Kai Adolf Jensen, professor i almindelig patologi
Høiby, N. 2016 I : Bibliotek for Læger. 208, 4, s. 344-361

Test and validation of methods to sample and detect human virus from environmental surfaces using norovirus as a model virus
Ibfelt, T., Frandsen, T., Permin, A., Andersen, L. P. & Schultz, A. C. apr. 2016 I : The Journal of hospital infection. 92, 4, s. 378-84 7 s.

CIED infection with either pocket or systemic infection presentation - complete device removal and long-term antibiotic treatment; long-term outcome
Ihlemann, N., Møller-Hansen, M., Salado-Rasmussen, K., Videbæk, R., Moser, C., Iversen, K. & Bundgaard, H. feb. 2016 I : Scandinavian cardiovascular journal : SCJ. 50, 1, s. 52-7 6 s.

Comparative Evaluation of Inoculation of Urine Samples with the Copan WASP® and BD Kiestra™ InoqulA™ Instruments
Iversen, J., Stendal, G., Gerdes, C. M., Hjortberg Meyer, C., Andersen, C. Ø. & Frimodt-Møller, N. feb. 2016 I : Journal of clinical microbiology. 54, 2, s. 328

Hyaluronic Acid Assays: Turbidimetric or Enzyme-Based Immune Assay? A Method Comparison Study
Itenov, T. S., Kirkby, N. S., Bestle, M. H., Nilsson, A. C., Erlandsen, E. J., Peters, L. & Jensen, J. U. S. okt. 2016 I : Journal of Clinical Laboratory Analysis. 30, 5, s. 524-8

The efficacy of pivmecillinam: 3 days or 5 days t.i.d against community acquired uncomplicated lower urinary tract infections - a randomized, double-blinded, placebo-controlled clinical trial study protocol
Jansaker, F., Frimodt-Møller, N., Bjerrum, L. & Dahl Knudsen, J. 1 dec. 2016 I : BMC Infectious Diseases. 16, 1, s. 727 7 s.

Post treatment antifungal resistance among colonizing Candida isolates in candidemia patients: results from a systematic multicenter study
Jensen, R. H., Johansen, H. K., Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C. 2016 I : Antimicrobial Agents and Chemotherapy.

Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application
Koren, K., Jensen, P. Ø. & Kühl, M. 21 jul. 2016 I : The Analyst. 141, 14, s. 4332-9 8 s.

Role of Multicellular Aggregates in Biofilm Formation
Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, P. Ø., Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, T. 22 mar. 2016 I : mBio. 7, 2, s. e00237

Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths-a prospective cohort study at a Danish University Hospital
Kvich, L., Jensen, P. Ø., Justesen, U. S. & Bjarnsholt, T. nov. 2016 I : Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 22, 11, s. 941-945 5 s.

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection
Leatham-Jensen, M. P., Mokszycki, M. E., Rowley, D. C., Deering, R., Camberg, J. L., Sokurenko, E. V., Tchesnokova, V. L., Frimodt-Møller, J., Krogfelt, K. A., Leth Nielsen, K., Frimodt-Møller, N., Sun, G. & Cohen, P. S. 16 jun. 2016 I : mSphere. 1, 1, s. e00055-15

Interspecific Bacterial Interactions are Reflected in Multispecies Biofilm Spatial Organization
Liu, W., Røder, H. L., Madsen, J. S., Bjarnsholt, T., Sørensen, S. J. & Burmølle, M. 2016 I : Frontiers in Microbiology. 7, s. 1366

Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections: a randomized, placebo-controlled study
Malhotra-Kumar, S. , Van Heirstraeten, L. , Coenen, S. , Lammens, C. , Adriaenssens, N. , Kowalczyk, A. , Godycki-Cwirko, M. , Bielicka, Z. , Hupkova, H. , Lannering, C. , Mölstad, S. , Fernandez-Vandellos, P. , Torres, A. , Parizel, M. , Ieven, M. , Butler, C. C. , Verheij, T. , Little, P. , Goossens, H. , GRACE study group ( Niels Frimodt-Møller, members) & 1 flere Frimodt-Møller, N. nov. 2016 I : The Journal of antimicrobial chemotherapy. 71, 11, s. 3258-3267 10 s.

Shaping the Growth Behaviour of Biofilms Initiated from Bacterial Aggregates
Melaugh, G., Hutchison, J., Kragh, K. N., Irie, Y., Roberts, A., Bjarnsholt, T., Diggle, S. P., Gordon, V. D. & Allen, R. J. 2016 I : P L o S One. 11, 3, s. e0149683

Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Mette, K., Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, T., Ciofu, O., Høiby, N. & Jensen, P. Ø. 2016 I : Pathogens and Disease. 74, s. ftv086

Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Mette, K., Mousavi, N., Sams, T., Bjarnsholt, T., Ciofu, O., Moser, C., Kühl, M., Høiby, N. & Jensen, P. Ø. feb. 2016 I : International journal of antimicrobial agents. 47, 2, s. 163-7 5 s.

Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis
Moser, C., Jensen, T. H., Schierbeck, J. & Høiby, N. 14 mar. 2016 I : Ugeskrift for laeger. 178, 11, s. V05150426

Early warning and prevention of pneumonia in acute leukemia by patient education, spirometry, and positive expiratory pressure: a randomized controlled trial
Møller, T., Moser, C., Adamsen, L., Rugaard , G., Jarden, M., Bøtcher, T. S., Wiedenbein, L. & Kjeldsen, L. 2016 I : American Journal of Hematology. 91, 3, s. 271-6 6 s.

New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits
Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, N. apr. 2016 I : The Journal of hospital infection. 92, 4, s. 337-339

Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes
Nielsen, S. M., Nørskov-Lauritsen, N., Bjarnsholt, T. & Meyer, R. L. 2016 I : Microorganisms. 4, 3, s. 33

Severe Human Parechovirus Infections in Infants and the Role of Older Siblings
Nielsen, N. M., Midgley, S. E., Nielsen, A. C. Y., Christiansen, C. B. & Fischer, T. K. 1 apr. 2016 I : American journal of epidemiology. 183, 7, s. 664-70 7 s.

The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms
Nilsson, M., Rybtke, M., Givskov, M., Høiby, N., Twetman, S. & Tolker-Nielsen, T. sep. 2016 I : International journal of antimicrobial agents. 48, 3, s. 298-304 7 s.

Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate
Norman, A., Ciofu, O., Amador, C. I., Høiby, N. & Jelsbak, L. 25 feb. 2016 I : Genome announcements. 4, 1, s. e00008-16

Simultaneous quantification of isoniazid, rifampicin, ethambutol and pyrazinamide by liquid chromatography/tandem mass spectrometry
Prahl, J. B., Lundqvist, M., Bahl, J. M. C., Johansen, I. S., Andersen, Å. B., Frimodt-Møller, N. & Cohen, A. S. 2016 I : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 124, 11, s. 1004-15

Comparing the harmful effects of nontuberculous mycobacteria and Gram negative bacteria on lung function in patients with cystic fibrosis
Qvist, T., Taylor-Robinson, D., Waldmann, E., Olesen, H. V., Hansen, C. R., Mathiesen, I. H., Høiby, N., Katzenstein, T. L., Smyth, R. L., Diggle, P. J. & Pressler, T. 2016 I : Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 15, 3, s. 380-5

Iodine excretion in school children in Copenhagen
Rasmussen, L. B., Kirkegaard-Klitbo, D. M., Laurberg, P., Jørgensen, T., Ovesen, L. & Perrild, H. maj 2016 I : Danish Medical Bulletin (Online). 63, 5

Whole genome sequencing as a tool for phylogenetic analysis of clinical strains of Mitis group streptococci
Rasmussen, L. H., Dargis, R., Højholt, K., Christensen, J. J., Skovgaard, O., Justesen, U. S., Rosenvinge, F. S., Moser, C., Lukjancenko, O., Rasmussen, S. & Nielsen, X. C. okt. 2016 I : European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 35, 10, s. 1615-25 11 s.

Proteome-wide antigen discovery of novel protective vaccine candidates against Staphylococcus aureus infection
Forfattergruppering (Peter Garred, Members) & Garred, P. 31 aug. 2016 I : Vaccine. 34, 38, s. 4602-9 8 s.

Absence of Pneumocystis jirovecii Colonization in Human Immunodeficiency Virus-Infected Individuals With and Without Airway Obstruction and With Undetectable Viral Load
Ronit, A., Klitbo, D. M., Kildemoes, A. O., Benfield, T., Gerstoft, J., Vestbo, J., Jensen, J. S., Kurtzhals, J. & Nielsen, S. D. nov. 2016 I : Open Forum Infectious Diseases. 3, 1, s. ofw044

Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections
Rudkjøbing, V. B., Thomsen, T. R., Xu, Y., Melton-Kreft, R., Ahmed, A., Eickhardt, S., Bjarnsholt, T., Poulsen, S. S., Nielsen, P. H., Earl, J. P., Ehrlich, G. D. & Moser, C. 8 nov. 2016 I : BMC Infectious Diseases. 16, 1, s. 652

Bacterial evolution in PCD and CF patients follows the same mutational steps
Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, K. G., Høiby, N., von Buchwald, C., Molin, S. & Johansen, H. K. 28 jun. 2016 I : Scientific Reports. 6, s. 28732

Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?
Sommer, L. M., Marvig, R. L., Luján, A., Koza, A., Pressler, T., Molin, S. & Johansen, H. K. 9 aug. 2016 I : BMC Genomics. 17, s. 589

Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils
Thomsen, K., Christophersen, L., Jensen, P. Ø., Bjarnsholt, T., Moser, C. & Høiby, N. 2 jul. 2016 I : Human vaccines & immunotherapeutics. 12, 7, s. 1690-9 10 s.

Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model
Thomsen, K., Christophersen, L. J., Bjarnsholt, T., Jensen, P. Ø., Moser, C. & Høiby, N. 2016 I : Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 15, 2, s. 171-8

The phagocytic fitness of leucopatches may impact the healing of chronic wounds
Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, N. & Moser, C. jun. 2016 I : Clinical and Experimental Immunology. 184, 3, s. 368-77 10 s.

Antibiotic treatment and mortality in patients with Listeria monocytogenes meningitis or bacteraemia
Thønnings, S., Knudsen, J. D., Schønheyder, H. C., Søgaard, M., Arpi, M., Gradel, K. O., Andersen, C. Ø. & Danish Collaborative Bacteraemia Network (DACOBAN) aug. 2016 I : Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 22, 8

Animal models of chronic wound care: the application of biofilms in clinical research
Trøstrup, H., Thomsen, K., Calum, H. P., Høiby, N. & Moser, C. E. 2016 I : Dove press (Chronic wound care management and research. 3, s. 123-132

S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus
Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, T., Høiby, N., Moser, C. & Ågren, S. P. M. jul. 2016 I : Archives of Dermatological Research. 308, 5, s. 347-55 9 s.

Alemtuzumab and soluble CD52 in patients with CLL
Vojdeman, F. J. 2016 København: Faculty of Health and Medical Sciences, University of Copenhagen. 115 s.

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin
Wassermann, T., Meinike Jørgensen, K., Ivanyshyn, K., Bjarnsholt, T., Khademi, S. M. H., Jelsbak, L., Høiby, N. & Ciofu, O. maj 2016 I : Microbiology (Reading, England). 162, 5, s. 865-75 11 s.



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