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Publications 2008

Denholt, C. L. Development of new radiolabelled PET-ligands for a cancer specifi c epidermal growth factor receptor and their applications for cancer diagnosis. PhD thesis defended September 17th 2008 at Rigshospitalet.

Frøkjær VG. Relating cerebral serotonin 2A receptor and serotonin transporter binding to personality and familial risk for mood disorder. København. PhD-thesis defended June 11th 2008 at Copenhagen University, The Faculty of Health.

Gerlach C. Visual object recognition and categoryspecifi city. DMSc thesis. Defended November 7th 2008 at Copenhagen University, The Faculty of Health.

Olesen, OV. “Motion correction on high resolution PET brain imaging”. MSc thesis. Defended October 10th 2008 at Rigshospitalet, Copenhagen University Hospital, The Faculty of Health and DTU.
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Andersen PA, Chakera AH, Klausen TL, Binderup T, Grossjohann HS, Friis E et al. Radiation exposure to surgical staff during F-18-FDG-guided cancer surgery. Eur J Nucl Med Mol Imaging 2008;35:624-9.

Bilde A, von Buchwald C, Therkildsen MH, Mortensen J, Kirkegaard J, Charabi B et al. Need for intensive histopathologic analysis to determine lymph node metastases when using sentinel node biopsy in oral cancer. Laryngoscope 2008;118:408-14.

Binderup T, Knigge U, Mellon Mogensen A, Palnæs Hansen C, Kjær A. Quantitative gene expression of somatostatin receptors and noradrenaline transporter underlying scintigraphic results in patients with neuroendocrine tumors. Neuroendocrinology 2008;87:223-32.

Chakera AH, Hansen LB, Lock-Andersen J, Drzewiecki KT, Hesse B. In-transit sentinel nodes must be found: implication from a 10-year follow-up study in melanoma. Melanoma Res 2008;18:359-64.

Crandall CG, Wilson TE, Marving J, Vogelsang TW, Kjær A, Hesse B et al. Effects of passive heating on central blood volume and ventricular dimensions in humans. J Physiol 2008;586:293-301.

Dümcke CW, Møller S. Autonomic dysfunction in cirrhosis and portal hypertension. Scand J Clin Lab Invest 2008;68:437-47.

Eckardt R, Andersen LI, Hesse B. Nuclear cardiology and coronary surgery. Panminerva Med 2008;50:119-27.

Engelholm SA, Højgaard L. Ny teknologi vil gavne danske kræftpatienter. Kronik. Berlingske Tidende 2008; 10. maj.

Erritzoe D, Rasmussen H, Kristiansen KT, Frøkjær VG, Haugbøl S, Pinborg L et al. Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive fi rst-episode schizophrenic patients. Neuropsychopharmacology 2008;33:2435-41.

Fisker Hag AM, Pedersen SF, Kjær A. Gene expression of LOX-1, VCAM-1, and ICAM-1 in pre-atherosclerotic mice. Biochem Biophys Res Commun 2008;377:689-93.

Frøkjær VG, Pinborg LH, Madsen J, de NijsR, Svarer C, Wagner A et al. Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans. J Nucl Med 2008;49:247-54.

Frøkjær VG, Mortensen EL, Nielsen FA, Haugbøl S, Pinborg LH, Adams KH et al. Frontolimbic serotonin 2A receptor binding in healthy subjects is associated with personality risk factors for affective disorder. Biol Psychiatry 2008;63:569-76.

Græbe M, Pedersen SF, Borgwardt L, Hojgaard L, Sillesen H, Kjær A. Molecular Pathology in Vul nerable Carotid Plaques: Correlation with [18]-Fluorodeoxyglucose Positron Emission Tomography (FDGPET). Eur J Vasc Endovasc Surg 2008; December 26;E-pub.

Gutte H, Leth PetersenC, Kjær A, Hesse B. Recent advances in nuclear cardiology. Panminerva Med 2008; 50:105-18.

Hall NM, Gjedde A, Kupers R. Neural mechanisms of voluntary and involuntary recall: a PET study. Behav Brain Res 2008;186:261-72.

Hansen CL, Hansen PR, Pedersen N, Poulsen HS, Gillings N, Kjær A. Identifi cation of amino acid residues in PEPHC1 important for binding to the tumorspecifi c receptor EGFRvIII. Chem Biol Drug Des 2008;72:273-8.

Hasselbach SG, Madsen K, Svarer C, Pinborg LH, Holm S, Paulson OB, Waldemar G, Knudsen GM. Reduced 5-HT2A receptor binding in patients with mild cognitive impairment. Neurobiol. Aging. 2008;29:1830-8.

Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ et al. EANM/ESC guidelines for radionuclide imaging of cardiac function. Eur J Nucl Med Mol Imaging 2008;35:851-85.

Hesse B, Petersen CL, Marcassa C, Bax JJ, Bengel F, Reyes E, et al. Myocardial perfusion scintigraphy. Exact and cost-effective coronary disease imagingsecondary publication. Ugeskr Laeger 2008;170:3637-9.

Hesse B, Heuer J, Gebauer E. Rehabilitation in the View of Small and Midsized Enterprises: Knowledge, Appreciation and Possibilities to Cooperate - Results of the KoRB-Project. Rehabilitation. 2008;47:324-33.

Hove JD, Rasmussen R, Freiberg J, Holm S, Kelbæk H, Kofoed KE. Clinical evaluation of iterative reconstruction (ordered-subset expectation maximization) in dynamic positron emission tomography: quantitative effects on kinetic modeling with N-13 ammonia in healthy subjects. J Nucl Cardiol 2008;15:530-4.

Højgaard L. Stronger medical research in Europe? Ugeskr Laeger 2008;170:3633.

Højgaard L. Kvoter ingen løsning for kvinder på KU. Universitetsavisen 2008;9:22-3.

Højgaard L, Børsting A, Kjærgaard L, Adamsen L, Overgaard Andersen N, Dirkinck-Holmfeld L, Goldschmidt L, Gram L, Hougaard Jensen SE. Forskningspolitiske udfordringer – nye veje for dansk sundhedsvidenskabelig forskning. Danmarks Forskningspolitiske Råd 2008:1-104.

Højgaard L et al. Advancing Systems Biology for Medical Applications. European Science Foundation, Strasbourg, France 2008:1-12.

Højgaard L et al. ESF-EMRC Position on the Proposed Revision of the Directive on the Protection of Animals Used for Experimental and Other Scientifi c Purposes. European Science Foundation, Strasbourg, France 2008:1-4.

Højgaard L et al. European Science Foundation calls for more and better medical imaging research. Medicine and Molecular Imaging 35. European Science Foundation, Strasbourg, France 2008(9):1749-57.

Højgaard L et al. Structural Medicine II: The Importance of Lipidomics for Health and Disease. European Science Foundation, Strasbourg, France 2008:1-8.

Højgaard L et al. Population Surveys and Biobanking. European Science Foundation, Strasbourg, France 2008:1-10.

Iversen HK, Holm S, Friberg L, Tfelt-Hansen P. Intracranial hemodynamics during intravenous infusion of glyceryl trinitrate. J Headache Pain 2008;9:177-80.

Jensen MM, Jørgensen JT, Binderup T, Kjær A. Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper. BMC Med Imaging 2008;8:16.

Johansen J, Buus S, Loft A, Keiding S, Overgaard M, Hansen HS et al. Prospective study of 18FDG-PET in the detection and management of patients with lymph node metastases to the neck from an unknown primary tumor. Results from the DAHANCA-13 study. Head Neck 2008;30:471-8.

Kalbitzer J, FrøKjær VG, Erritzoe D, Svarer C, Cumming P, Nielsen FA et al. The personality trait openness is related to cerebral 5-HTT levels. Neuroimage 2008;E-pub.

Kalialis LV, Drzewiecki KT, Mohammadi M, Mehlsen AB, Klyver H. Spontaneous regression of metastases from malignant melanoma: a case report. Melanoma Res. 2008;18:279-83.

Keller SH, Lauze F, Nielsen M. Deinterlacing using variational methods. IEEE Trans Image Process 2008;17:2015-28.

Knigge U, Hansen CP, Gustafsen J, Kjær A. Endoscopic ultrasonography in patients with suspected neuroendocrine tumors. Ugeskr Laeger 2008;170:2469.

Kornum BR, Lind NM, Gillings N, Marner L, Andersen F, Knudsen GM. Evaluation of the novel 5-HT4 receptor PET ligand [11C]SB207145 in the Gottingen minipig. J Cereb Blood Flow Metab 2009;29:186-96.

Kristiansen C, Loft A, Berthelsen AK, Graff J, Lindebjerg J, Bisgaard C et al. PET/CT and histopathologic response to preoperative chemoradiation therapy in locally advanced rectal cancer. Dis Colon Rectum 2008;51:21-5.

Kristoffersen US, Lebech AM, Gerstoft J, Hesse B, Petersen CL, Gutte H, et al. Right and left cardiac function in HIV-infected patients investigated using radionuclide ventriculography and brain natriuretic peptide: a 5-year follow-up study. HIV Med 2008;9:180-6.

Kupers R, Frøkjær VG, Naert A, Christensen R, Budtz-Joergensen E, Kehlet H et al. A PET [18F]altanserin study of 5-HT2A receptor binding in the human brain and responses to painful heat stimulation. Neuroimage 2009;44:1001-7.

Lebech AM, Kristoffersen US, Wiinberg N, Kofoed K, Andersen O, Hesse B et al. Coronary and peripheral endothelial function in HIV patients studied with positron emission tomography and fl ow-mediated dilation: relation to hypercholesterolemia. Eur J Nucl Med Mol Imaging 2008;35:2049-58.

Lindegren S, Frost S, Back T, Haglund E, Elgqvist J, Jensen H. Direct procedure for the production of 211At-labeled antibodies with an epsilon-lysyl-3-(trimethylstannyl)benzamide immuno¬conjugate. J Nucl Med 2008;49:1537-45.

Lindquist SG, Holm IE, Schwartz M, Law I, Stokholm J, Batbayli M et al. Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation. Eur J Neurol 2008;15:377-85.

Louring-Andersen J, Law I. The effects of bone erosion from aortic aneurysm on the regional uptake of FDG. Clin Nucl Med 2008;33:482-3.

Madsen JL, Graff J. Effects of the H2-receptor antagonist ranitidine on gastric motor function after a liquid meal in healthy humans. Scand J Clin Lab Invest 2008;68:681-4.

Marcassa C, Bax JJ, Bengel F, Hesse B, Petersen CL, Reyes E, et al. Clinical value, cost-effectiveness, and safety of myocardial perfusion scintigraphy: a position statement. Eur Heart J 2008;29:557-63.

Marner L, Knudsen GM, Haugbøl S, Holm S, Baare W, Hasselbalch SG. Longitudinal assessment of cerebral 5-HT(2A) receptors in healthy elderly volunteers: an [(18)F]-altanserin PET study. Eur J Nucl Med Mol Imaging 2008;E-pub

Mortensen J. Lung scintigraphy-SPECT/CT. The Danish Society of Clinical Physiology and Nuclear Medicine. Ugeskr Laeger 2008;170:1040.

Naert AL, Kehlet H, Kupers R. Characterization of a novel model of tonic heat pain stimulation in healthy volunteers. Pain 2008;138:163-71.

Pinborg LH, Arfan H, Haugbøl S, Kyvik KO, Hjelmborg JV, Svarer C et al. The 5-HT2A receptor binding pattern in the human brain is strongly genetically determined. Neuroimage 2008;40:1175-80.

Ptito M, Schneider FC, Paulson OB, Kupers R. Alterations of the visual pathways in congenital blindness. Exp Brain Res 2008;187:41-9.

Ptito M, Fumal A, de Noordhout AM, Schoenen J, Gjedde A, Kupers R. TMS of the occipital cortex induces tactile sensations in the fi ngers of blind Braille readers. Exp Brain Res 2008;184:193-200.

Ptito M, Kupers R. The Neurology of Consciousness. Elsevier. 2008:360-74.

Risum S, Høgdall C, Loft A, Berthelsen AK, Høgdall E, Nedergaard L et al. Prediction of sub-optimal primary cytoreduction in primary ovarian cancer with combined positron emission tomography/computed tomography—a prospective study. Gynecol Oncol 2008;108:265-70.

Sørensen JB, Ravn J, Loft A, Brenø J, Berthelsen AK. Preoperative staging of mesothelioma by 18Ffl uoro-2-deoxy-D-glucose positron emission tomography/ computed tomography fused imaging and mediastinoscopy compared to pathological fi ndings after extrapleural pneumonectomy. Eur J Cardiothorac Surg 2008;34:1090-6.

Stauss J, Franzius C, Pfl uger T, Juergens KU, Biassoni L, Begent J, Kluge R, Amthauer H, Voelker T, Højgaard L, Barrington S, Hain S, Lynch T, Hahn K. Guidelines for 18F-FDG PET and PET-CT imaging in pediatric oncology. Eur J Nucl Med Mol Imaging 2008;35:1581-8.

Strålman K, Mollerup CL, Kristoffersen US, Elberg JJ. Long-term outcome after mastectomy wit immediate breast reconstruction. Acta Oncol. 2008;47:704-8.

Strålman K, Kristoffersen US, Galatius H, Lanng C. Factors infl uencing sentinel lymph node identifi cation failure in breast cancer surgery. Breast 2008;17:167-71.

Tagil K, Marving J, Lomsky M, Hesse B, Edenbrandt L. Use of neural networks to improve quality control of interpretations in myocardial perfusion imaging. Int J Cardiovasc Imaging 2008;24:841-8.

Tagil K, Bondouy M, Chaborel JP, Djaballah W, Franken PR, Grandpierre S et al. A decision support system improves the interpretation of myocardial perfusion imaging. Eur J Nucl Med Mol Imaging 2008;35:1602-7.

Therkelsen SK, Grønning BA, Kjær A, Svendsen JH, Boje JensenG. ANP and BNP in atrial fi brillation before and after cardioversion-and their relationship to cardiac volume and function. Int J Cardiol 2008;127:396-9.

Tuunanen H, Engblom E, Naum A, Naagren K, Scheinin M, Hesse B et al. Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefi ts in idiopathic dilated cardiomyopathy. Circulation 2008;118:1250-8.

Vogelsang TW, Jensen RJ, Hesse B, Kjær A. BNP cannot replace gated equilibrium radionuclide ventriculography in monitoring of anthracycline-induced cardiotoxity. Int J Cardiol 2008;124:193-7.

Vogelsang TW, Hanel B, Kristoffersen US, Petersen CL, Mehlsen J, Holmquist N et al. Effect of eight weeks of endurance exercise training on right and left ventricular volume and mass in untrained obese subjects: a longitudinal MRI study. Scand J Med Sci Sports 2008;18:354-9.